Pulmonary surfactant: phase behavior and function
B Piknova, V Schram, SB Hall - Current opinion in structural biology, 2002 - Elsevier
Pulmonary surfactant functions by first flowing rapidly into the alveolar air/water interface, but
then resisting collapse from the surface when the adsorbed interfacial film is compressed …
then resisting collapse from the surface when the adsorbed interfacial film is compressed …
The biophysical function of pulmonary surfactant
S Rugonyi, SC Biswas, SB Hall - Respiratory physiology & neurobiology, 2008 - Elsevier
Pulmonary surfactant lowers surface tension in the lungs. Physiological studies indicate two
key aspects of this function: that the surfactant film forms rapidly; and that when compressed …
key aspects of this function: that the surfactant film forms rapidly; and that when compressed …
[HTML][HTML] Pulmonary surfactant: functions and molecular composition
J Goerke - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 1998 - Elsevier
This review briefly notes recent findings important for understanding the surface mechanical
functions of pulmonary surfactant. Currently known surfactant-specific proteins and lipids are …
functions of pulmonary surfactant. Currently known surfactant-specific proteins and lipids are …
Molecular interactions in pulmonary surfactant films
J Pérez-Gil - Neonatology, 2002 - karger.com
Pulmonary surfactant is a lipid-protein complex which has the essential physiological role of
stabilizing the respiratory surface of lungs against collapse. To achieve this function …
stabilizing the respiratory surface of lungs against collapse. To achieve this function …
Effect of acute lung injury on structure and function of pulmonary surfactant films
AK Panda, K Nag, RR Harbottle… - American journal of …, 2004 - atsjournals.org
The structural and functional alterations in pulmonary surfactant that occur during acute lung
injury were studied using rat lung surfactant large aggregates (LA) isolated from normal …
injury were studied using rat lung surfactant large aggregates (LA) isolated from normal …
Influence of liquid-layer thickness on pulmonary surfactant spreading and collapse
TA Siebert, S Rugonyi - Biophysical journal, 2008 - cell.com
Pulmonary surfactant spreads on the thin (∼ 0.1μm) liquid layer that lines the alveoli,
forming a film that reduces surface tension and allows normal respiration. Pulmonary …
forming a film that reduces surface tension and allows normal respiration. Pulmonary …
Lateral phase separation in interfacial films of pulmonary surfactant
BM Discher, KM Maloney, WR Schief, DW Grainger… - Biophysical journal, 1996 - cell.com
To determine if lateral phase separation occurs in films of pulmonary surfactant, we used
epifluorescence microscopy and Brewster angle microscopy (BAM) to study spread films of …
epifluorescence microscopy and Brewster angle microscopy (BAM) to study spread films of …
Pulmonary surfactant: a mighty thin film
F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
Phase transitions in films of lung surfactant at the air-water interface
K Nag, J Perez-Gil, MLF Ruano, LAD Worthman… - Biophysical journal, 1998 - cell.com
Pulmonary surfactant maintains a putative surface-active film at the air-alveolar fluid
interface and prevents lung collapse at low volumes. Porcine lung surfactant extracts (LSE) …
interface and prevents lung collapse at low volumes. Porcine lung surfactant extracts (LSE) …
[HTML][HTML] More than a monolayer: relating lung surfactant structure and mechanics to composition
C Alonso, T Alig, J Yoon, F Bringezu, H Warriner… - Biophysical …, 2004 - cell.com
Survanta, a clinically used bovine lung surfactant extract, in contact with surfactant in the
subphase, shows a coexistence of discrete monolayer islands of solid phase coexisting with …
subphase, shows a coexistence of discrete monolayer islands of solid phase coexisting with …