Adiponectin in health and disease

DK Oh, T Ciaraldi, RR Henry - Diabetes, obesity and …, 2007 - Wiley Online Library
Adipose tissue is an active metabolic tissue that secretes multiple metabolically important
proteins, known as adipokines. Adiponectin is an important adipokine because of its …

Adiponectin: Identification, physiology and clinical relevance in metabolic and vascular disease

Y Matsuzawa - Atherosclerosis supplements, 2005 - Elsevier
Adiponectin is the most abundant adipose-specific protein. Its expression is reduced in
obesity, insulin resistance and type 2 diabetes, and plasma concentrations are inversely …

Physiological, pharmacological, and nutritional regulation of circulating adiponectin concentrations in humans

MM Swarbrick, PJ Havel - Metabolic syndrome and related …, 2008 - liebertpub.com
Adiponectin is an adipocyte hormone that links visceral adiposity with insulin resistance and
atherosclerosis. It is unique among adipocyte-derived hormones in that its circulating …

The role of adiponectin in obesity, diabetes, and cardiovascular disease

J Kawano, R Arora - Journal of the cardiometabolic syndrome, 2009 - Wiley Online Library
Nearly 1 in 4 adults in the United States is obese. The connection between obesity and
insulin resistance, type 2 diabetes, and cardiovascular disease is a well researched one …

Modulation of adiponectin as a potential therapeutic strategy

S Lim, MJ Quon, KK Koh - Atherosclerosis, 2014 - Elsevier
Adiponectin is produced predominantly by adipocytes and plays an important role in
metabolic and cardiovascular homeostasis through its insulin-sensitizing actions and anti …

Mechanisms of adiponectin regulation and use as a pharmacological target

SA Phillips, JT Kung - Current opinion in pharmacology, 2010 - Elsevier
Adiponectin is an insulin-sensitizing and anti-inflammatory fat cell hormone that has
immense potential as a therapeutic target for a multitude of obesity-associated diseases …

Adiponectin, a unique adipocyte-derived factor beyond hormones

N Maeda, T Funahashi, Y Matsuzawa, I Shimomura - Atherosclerosis, 2020 - Elsevier
Visceral fat accumulation has a marked impact on atherosclerotic cardiovascular diseases
and metabolic syndrome clustering diabetes, dyslipidemia, and hypertension. Adiponectin …

Adiponectin: regulation of its production and its role in human diseases

A Shehzad, W Iqbal, O Shehzad, YS Lee - Hormones, 2012 - Springer
Adiponectin is a white and brown adipose tissue hormone, also known as gelatin-binding
protein-28 (GBP28), AdipoQ, adipocyte complement-related protein (ACRP30), or apM1 …

Adiponectin: a key adipocytokine in metabolic syndrome

Y Okamoto, S Kihara, T Funahashi… - Clinical …, 2006 - portlandpress.com
The metabolic syndrome, a cluster of metabolic disorders often associated with visceral
obesity, increases cardiovascular mortality and morbidity. As the body's largest endocrine …

Adiponectin-its role in metabolism and beyond

N Stefan, M Stumvoll - Hormone and Metabolic Research, 2002 - thieme-connect.com
Adiponectin is a recently identified adipose tissue-derived protein (adipocytokine) with
important metabolic effects. It is exclusively expressed in adipose tissue and released into …