Acute pancreatitis is an acute inflammatory process localized in the pancreatic gland that
frequently involves peripancreatic tissues. It is still under investigation why an episode of …

Acute pancreatitis starts as a local inflammation of the pancreatic tissue but often leads to
the systemic inflammatory response syndrome and death by multiple organ failure. Pro …

Histone acetylation via CBP/p300 coordinates the expression of proinflammatory cytokines
in the activation phase of inflammation, particularly through mitogen-activated protein …

Acute pancreatitis is an inflammation initially localized in the pancreatic gland which may
lead to local and systemic complications. The development of severe acute pancreatitis is …

Severe acute pancreatitis causes a high incidence of mortality due to the systemic
inflammatory response syndrome leading to multiple organ failure. At present, there is no …

Acute pancreatitis is an inflammatory process of the pancreatic gland that eventually may
lead to a severe systemic inflammatory response. A key event in pancreatic damage is the …

Acute pancreatitis (AP) is a severe disease with a high prevalence and 3 to 15% mortality
worldwide, which can represent an important challenge for the physician. Oxidative stress …

Significance: Oxidative stress plays an important role in the pathogenesis of both acute and
chronic pancreatitis. Although its impact is well investigated and has been studied clinically …

Mitogen-activated protein kinases (MAPKs) are considered major signal transducers early
during the development of acute pancreatitis. Pentoxifylline is a phosphodiesterase inhibitor …

Oxidative stress is considered to be an important regulator of the pathogenesis of acute
pancreatitis. Reactive oxygen species (ROS) regulate the activation of inflammatory …