Previous studies in animals and humans have shown that selenium compounds can prevent
cancer development. In this work we studied the tumor preventive effect of selenium …

Studies were conducted in vivo with regenerating liver and in vitro with mammalian cells to
determine the effects of selenium on cell proliferation and the stages of the cell cycle …

Although the earlier literature regarding selenium stressed its toxicity, especially its role in
carcinogenesis, there is an increasingly held view that selenium is an essential trace …

Inhibition of Carcinogenesis There have been approximately 60 publications in the scientific
literature which have examined the effects of selenium as a chemopreventive agent [for …

The experiments reported herein examined the inhibitory role of selenium in chemical
carcinogen-induced mouse mammary tumorigenesis. The results from four different …

Chemical carcinogenesis can be characterized by a sequence of events leading to the
development of tumors. Selenium (Se) inhibition of colon, liver, and lung carcinogens is …

Selenium is an essential micronutrient mineral found mainly in soils and has been shown to
prevent certain cancers in humans and animals. However, the dose and effects of selenium …

Selenium is increasingly recognized as a versatile anticarcinogenic agent. Its protective
functions cannot be solely attributed to the action of glutathione peroxidase. Instead …

The present studies demonstrate that the ability of supplemental selenite to alter the in vitro
growth of canine mammary tumor cell line 13 was dependent on the quantity and duration of …

Selenium has been reported to affect glutathione (GSH) concentrations in short-term animal-
feeding experiments. Given the central role that this tripeptide plays in maintaining cellular …