Tumor angiogenesis: insights and innovations

F Nussenbaum, IM Herman - Journal of oncology, 2010 - Wiley Online Library
Angiogenesis is a vital process resulting in the formation of new blood vessels. It is normally
a highly regulated process that occurs during human development, reproduction, and …

[HTML][HTML] Tumor angiogenesis: Current challenges and therapeutic opportunities

FH Al-Ostoot, S Salah, HA Khamees… - Cancer Treatment and …, 2021 - Elsevier
Angiogenesis plays an important role in the development of cancer since it allows for the
delivery of oxygen, nutrients, and growth factors as well as tumor dissemination to distant …

Treating cancer by inhibiting angiogenesis: new hopes and potential pitfall

J Rak, RS Kerbel - Cancer and Metastasis Reviews, 1996 - Springer
Angiogenesis is essential for progressive solid tumor growth and thus constitutes a very
promising therapeutic target. Recent developments in understanding of the molecular …

Angiogenesis as a target for tumor treatment

G Gastl, T Hermann, M Steurer, J Zmija, E Gunsilius… - Oncology, 1997 - karger.com
Angiogenesis is a key step in tumor growth, invasion and metastasis. Thus, antiangiogenic
therapy was postulated to be an attractive approach for antitumor treatment. Based on …

Tumor angiogenesis: biology and therapeutic prospects.

SR Harris, UP Thorgeirsson - In Vivo (Athens, Greece), 1998 - europepmc.org
Angiogenesis is now recognized as a critical process in tumor progression and is required
for solid tumors to grow beyond a few millimeters in size. The transition from a non …

Angiogenesis and current antiangiogenic strategies for the treatment of cancer

R Oklu, TG Walker, S Wicky, R Hesketh - Journal of vascular and …, 2010 - Elsevier
Angiogenesis is a complex process critical for embryonic development and for survival. It is
also a critical player in many pathologic processes, most notably in neoplasia. The cell …

Inhibitors of angiogenesis in a clinical perspective

EE Voest - Anti-Cancer Drugs, 1996 - journals.lww.com
Inhibition of angiogenesis or preventing the outgrowth of new blood vessels towards a tumor
is one of the most promising areas of anticancer drug development. Several angiogenesis …

The role of angiogenesis in cancer treatment

M Rajabi, SA Mousa - Biomedicines, 2017 - mdpi.com
A number of anti-angiogenesis drugs have been FDA-approved and are being used in
cancer treatment, and a number of other agents are in different stages of clinical …

Tumoral angiogenesis: physiopathology, prognostic value and therapeutic perspectives

T Andre, E Chastre, L Kotelevets… - La Revue de …, 1998 - europepmc.org
Angiogenesis activation plays a crucial role in tumoral growth and metastases
dissemination. This review summarizes and analyzes current knowledge on molecular …

Angiogenesis in cancer: molecular mechanisms, clinical impact

ME Eichhorn, A Kleespies, MK Angele… - … Archives of Surgery, 2007 - Springer
Background Angiogenesis, the formation of new blood vessels from the endothelium of the
existing vasculature, is fundamental in tumor growth, progression, and metastasis. Inhibiting …