Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease with increasing
mortality and poor prognosis. The current understanding of the role of long noncoding RNAs …

Idiopathic pulmonary fibrosis (IPF) is a fatal disease that destroys the structure and function
of the lungs. Risk factors include advanced age and genetic predisposition. However …

Background Epithelial-mesenchymal interactions are critical in regulating many aspects of
vertebrate embryo development, and for the maintenance of homeostatic equilibrium in adult …

Lung epithelial-mesenchymal transition (EMT) plays an important role in silicosis fibrosis.
The reverse process of EMT is mesenchymal-epithelial transition (MET), which is viewed as …

Fibrosis in the lungs usually occurs in the initial phase of acute respiratory distress
syndrome (ARDS), which exacerbates poor prognosis among patients. MicroRNAs (miRs) …

Rationale: Alveolar epithelial cell (AEC) injury and dysregulated repair are implicated in the
pathogenesis of pulmonary fibrosis. Endoplasmic reticulum (ER) stress in AEC has been …

Idiopathic pulmonary fibrosis (IPF) is considered to be an ailment of the lungs that cannot be
cured, wherein the lung tissues are characterized by increased thickness and stiffness …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal fibrotic lung disease
characterized by profound changes in stem cell differentiation, epithelial cell phenotypes …

Background In pressure overload, profibrotic gene expression and cardiac fibrosis are more
pronounced in males than in females. Sex-specific and estrogen-dependent regulation of …

Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease with irreversible
loss of lung tissue and function. Myofibroblasts in the lung are key cellular mediators of IPF …