The amyloid β-peptides (Aßs) are the main protein components of amyloid deposits in
Alzheimer's disease (AD). Detailed knowledge of the structure and assembly dynamics of Aß …

Alzheimer's disease (AD) is characterized by fibrillar deposits of amyloid-β (Aβ) peptides
and neurofibrillary tangles of Tau proteins. Aβ peptides are composed of 37–49 residues …

Abnormal aggregation of amyloid β (Aβ) peptides into fibrils plays a critical role in the
development of Alzheimer's disease. A two-stage “dock-lock” model has been proposed for …

Aβ 16–22 is believed to have critical role in early aggregation of full length amyloids that are
associated with the Alzheimer's disease and can aggregate to form amyloid fibrils. However …

High-resolution structures of oligomers formed by the β-amyloid peptide, Aβ, are important
for understanding the molecular basis of Alzheimer's disease. Dimers of Aβ are linked to the …

As the primary toxic species in the etiology of Alzheimer disease (AD) are low molecular
weight oligomers of Aβ, it is crucial to understand the structure of Aβ oligomers for gaining …

The aggregation of the amyloid β (Aβ) peptide is a major hallmark of Alzheimer's disease.
This peptide can aggregate into oligomers, proto-fibrils and mature fibrils, which eventually …

Using a variant of Hamilton-replica-exchange, we study for wild type and Iowa mutant Aβ 40
the conversion between fibrils with antiparallel β-sheets and such with parallel β-sheets. We …

Alzheimer's disease is a debilitating neurodegenerative disorder associated with the
abnormal self-assembly of amyloid-β (Aβ) peptides into fibrillar species. N-methylated …

Amyloid aggregation is linked to a number of neurodegenerative syndromes, the most
prevalent one being Alzheimer's disease. In this pathology, the β‐amyloid peptides (Aβ) …