The endogenous and exogenous mechanisms for protection from ultraviolet irradiation in the lens

CMH Colitz, JA Bomser… - International …, 2005 - journals.lww.com
Ultraviolet (UV) irradiation can damage the lens and over the lifetime of the individual
contributes to the development of age-related cataract. Cataracts occur in all species …

Solar ultraviolet radiation cataract

S Löfgren - Experimental eye research, 2017 - Elsevier
Despite being a treatable disease, cataract is still the leading cause for blindness in the
world. Solar ultraviolet radiation is epidemiologically linked to cataract development, while …

A review of the evidence that ultraviolet irradiation is a risk factor in cataractogenesis

KR Hightower - Documenta ophthalmologica, 1995 - Springer
There are two approaches to the question of whether solar radiation contributes to human
cataract. The first, epidemiological studies, investigates correlations between man's …

Action spectrum for cytotoxicity in the UVA-and UVB-wavelength region in cultured lens epithelial cells.

UP Andley, RM Lewis, JR Reddan… - … & visual science, 1994 - iovs.arvojournals.org
PURPOSE: This study was done to quantitate the biologic effects of different wavelengths of
radiation in the UVA-and UVB-wavelength region on cultured rabbit lens epithelial cells …

Differential radiosensitivity of uveal melanoma cell lines after X-rays or carbon ions radiation

A Calipel, A Lux, S Guérin, JL Lefaix… - … & Visual Science, 2015 - iovs.arvojournals.org
Purpose.: We compared the radiosensitivity of uveal melanoma (UM) cell lines after x-ray or
carbon-ions radiation (C-ions). Methods.: We characterized the radiosensitivity toward x-rays …

Ionizing radiation sensitivity of the ocular lens and its dose rate dependence

N Hamada - International Journal of Radiation Biology, 2017 - Taylor & Francis
Abstract Purpose: In 2011, the International Commission on Radiological Protection reduced
the threshold for the lens effects of low linear energy transfer (LET) radiation. On one hand …

Oxidative and nitrative stress-related changes in human lens epithelial cells following exposure to X-rays

S Bahia, E Blais, S Murugkar, V Chauhan… - … journal of radiation …, 2018 - Taylor & Francis
Purpose: There is limited understanding of the mechanistic effects of ionizing radiation (IR)
exposure in cataract formation. In this study, we explored the effects of IR on reactive …

Lens epithelium: a primary target of UVB irradiation

KR Hightower, JR Reddan, JP McCready… - Experimental eye …, 1994 - Elsevier
Cultured rabbit lenses and cultured rabbit lens epithelial cells were irradiated with UV to
correlate morphological changes in the epithelium with physiological changes in the whole …

The role of age, sex and steroid sex hormones in radiation cataractogenesis

JR Dynlacht - Radiation research, 2013 - meridian.allenpress.com
It is critical to identify and gain a better understanding of the factors that enhance or reduce
the risk of cataractogenesis, to minimize the possibility of occurrence after deliberate (eg …

Ionizing radiation response of primary normal human lens epithelial cells

N Hamada - PLoS One, 2017 - journals.plos.org
Whilst the cataractogenic potential of ionizing radiation has been known for over the past
120 years, little is known about radiation responses of lens cells. Our previous work was the …