We previously found that lenses lacking the Acvr1 gene, which encodes a bone
morphogenetic protein (BMP) receptor, had abnormal proliferation and cell death in …

Studies were conducted on the effect of age on the production of fragmented nuclei in
meridional row (MR) cells following ocular exposure to X radiation. It was found that …

The authors review the available evidence supporting the possible role of oxidative stress in
cataract formation from an epidemiological and a clinical point of view. They discuss in more …

ABSTRACT UV‐A radiation produces cataract in animals, enhances photoaging of the lens
and skin and increases the phototoxicity of drugs. However, the nature of genes that are …

Cataract is the first of the five immediate priority areas for the global initiative to eliminate
avoidable blindness by the year 2020, Vision 2020. 1 Cataract was chosen because it is the …

The restitution of normal fibergenesis that occurs in stationary radiation cataracts provides a
unique opportunity to study the cytopathomechanism of radiocataractogenesis. Previous …

Purpose.: To study the effect of age on the morphologic and biochemical alterations induced
by in vivo exposure of ultraviolet radiation (UV). Methods.: Young and old C57BL/6 mice …

Lens homeostasis and transparency are dependent on the function and intercellular
communication of its epithelia. While the lens epithelium is uniquely equipped with …

Purpose: DNA damage has been described in the human cataractous lens epithelium, and
oxidative stress generated by UV radiation and endogenous metabolic processes has been …

Exposure to ultraviolet radiation (UVR) and reactive oxygen species (ROS) can damage the
human lens and contribute to cataract formation. Recent evidence suggests that apoptosis in …