Background: The native crystalline lens is the principal shield against ultraviolet radiation
(UV), damage to the human retina. Every year in the United States, more than one million …

Cataract is the leading cause of blindness worldwide and accounts for approximately half of
all forms of vision loss. Currently, the only way to treat cataracts is by surgery. However, with …

Cataract is the leading cause of blindness all over the world. An exact etiology and
mechanism of cataract formation may be diffi cult to ascertain in most of the cases. However …

Introduction Mitotic activity in the lens epithelium of laboratory animals is suppressed after
ionizing radiation, 1-4 and the extent and duration of this suppression varies with the …

The apoptosis of human lens epithelial cells (HLECs) is a characteristic change that occurs
during the development of cataracts. Ultraviolet B (UVB) is known to induce the generation …

In recent years, there has been renewed interest in the association between DNA damage to
the lens epithelium and the development of lens opacities. Although a number of in vitro …

Exactly a century after Röntgen's discovery of X rays, I entered a university to major in
radiological sciences. At that time, I felt that, despite extensive use and indispensable roles …

Earlier studies in our laboratory showed that 24 hr after X-irradiation, epithelial cells of early
postnatal rat lenses increased in volume. Three days after X-irradiation, the underlying lens …

PURPOSE: Previous work has shown that exposure of lens epithelial cells or rabbit eyes in
vivo to ultraviolet B (UVB) radiation enhanced prostaglandin (PG) E2 synthesis. Such …