Circulating permeability factors in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis

ET McCarthy, M Sharma, VJ Savin - Clinical Journal of the …, 2010 - journals.lww.com
Circulating permeability factors may be important in idiopathic nephrotic syndrome (INS)
including focal segmental glomerulosclerosis (FSGS) and in recurrence after renal …

The focal segmental glomerulosclerosis permeability factor: biochemical characteristics and biological effects

M Sharma, R Sharma, ET McCarthy… - … Biology and Medicine, 2004 - journals.sagepub.com
Focal segmental glomerulosclerosis (FSGS) is characterized by steroid resistant nephrotic
syndrome and progression to end-stage renal disease. Proteinuria in certain patients with …

Galactose binds to focal segmental glomerulosclerosis permeability factor and inhibits its activity

VJ Savin, ET McCarthy, R Sharma, D Charba… - Translational …, 2008 - Elsevier
Focal segmental glomerulosclerosis (FSGS) is associated with circulating permeability
activity (Palb) and recurs after transplantation in about 30% of patients. The FS permeability …

Permeability factors in idiopathic nephrotic syndrome: historical perspectives and lessons for the future

RJ Maas, JK Deegens, JF Wetzels - Nephrology Dialysis …, 2014 - academic.oup.com
The term idiopathic nephrotic syndrome (iNS) traditionally covers minimal change disease
and primary focal segmental glomerulosclerosis (FSGS), now thought to be separate …

“The FSGS Factor”: Enrichment and: in Vivo: Effect of Activity from Focal Segmental Glomerulosclerosis Plasma

M Sharma, R Sharma, ET McCarthy… - Journal of the American …, 1999 - journals.lww.com
A circulating causative factor has been postulated in focal segmental glomerulosclerosis
(FSGS). It has been shown that serum or plasma from some FSGS increases glomerular …

[HTML][HTML] Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis

VJ Savin, R Sharma, M Sharma… - … England Journal of …, 1996 - Mass Medical Soc
Background Heavy proteinuria and progressive renal injury recur after transplantation in up
to 40 percent of patients with renal failure caused by idiopathic focal segmental …

A circulating permeability factor in focal segmental glomerulosclerosis: the hunt continues

T Wada, M Nangaku - Clinical Kidney Journal, 2015 - academic.oup.com
Primary focal segmental glomerulosclerosis (FSGS) is one of the major causes of steroid-
resistant nephrotic syndrome, and renal prognosis in patients with steroid-resistant FSGS is …

Plasmapheresis in the treatment of steroid-resistant focal segmental glomerulosclerosis in native kidneys

SM Feld, P Figueroa, V Savin, CC Nast… - American journal of …, 1998 - ajkd.org
A circulating glomerular capillary albumin permeability factor (P (alb)) has been implicated
in the pathogenesis of focal segmental glomerulosclerosis (FSGS), which recurs in …

PROTEINURIA AFTER INJECTION OF HUMAN FOCAL SEGMENTAL GLOMERULOSCLEROSIS FACTOR12

M Sharma, R Sharma, SR Reddy, ET McCarthy… - …, 2002 - journals.lww.com
Background. Recurrent focal segmental glomerulosclerosis (FSGS) is heralded by
proteinuria that may remit after treatment with plasmapheresis or immunoadsorption. Study …

Plasmapheresis reduces proteinuria and serum capacity to injure glomeruli in patients with recurrent focal glomerulosclerosis

ML Artero, R Sharma, VJ Savin, F Vincenti - American Journal of Kidney …, 1994 - Elsevier
To test the hypothesis that a circulating mediator is associated with recurrent idiopathic focal
glomerulosclerosis (FGS), we studied the effect of plasmapheresis on reducing proteinuria …