[HTML][HTML] Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression

WX Chen, DD Wang, B Zhu, YZ Zhu, L Zheng… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Exosome-mediated intercellular communication is considered to be an effective mode for
malignant cells to transform biological behaviors in stromal cells. However, the mechanisms …

Tumor‐derived exosomal miR‐148b‐3p mediates M2 macrophage polarization via TSC2/mTORC1 to promote breast cancer migration and invasion

C Hao, Z Sheng, W Wang, R Feng, Y Zheng… - Thoracic …, 2023 - Wiley Online Library
Background Emerging evidence has revealed that tumor‐associated macrophages (TAMs)
and exosomes play a crucial role in the microenvironment for tumor growth. However, the …

Cancer-derived exosomal miR-7641 promotes breast cancer progression and metastasis

S Shen, Y Song, B Zhao, Y Xu, X Ren, Y Zhou… - Cell communication and …, 2021 - Springer
Background Intercellular communication is crucial for breast cancer progression and
metastasis. However, the role of cancer-derived exosomes and their crucial microRNA …

Breast cancer-derived exosomes regulate cell invasion and metastasis in breast cancer via miR-146a to activate cancer associated fibroblasts in tumor …

SS Yang, S Ma, H Dou, F Liu, SY Zhang, C Jiang… - Experimental cell …, 2020 - Elsevier
Objective To explore the effects of breast cancer (BC)-derived exosomes on invasion and
migration of BC cells. Methods Exosomes (Exo-MA, Exo-M7, Exo-M1) were extracted from …

In vitro and in vivo evaluation of anti-tumoral effect of M1 phenotype induction in macrophages by miR-130 and miR-33 containing exosomes

M Moradi-Chaleshtori, M Bandehpour, S Soudi… - Cancer Immunology …, 2021 - Springer
In the tumor microenvironment, macrophages polarize into the M2 phenotype to facilitate
tumorigenesis. Tumor-derived exosomes can act as mediators between the tumor …

Exosomes derived from hypoxic epithelial ovarian cancer deliver microRNA-940 to induce macrophage M2 polarization

X Chen, X Ying, X Wang, X Wu, Q Zhu… - Oncology …, 2017 - spandidos-publications.com
Hypoxia is a common feature of solid tumors. It is closely related to tumor progression.
Exosomal microRNAs derived from cancers are considered to be mediators between cancer …

Melanoma-derived exosomes endow fibroblasts with an invasive potential via miR-21 target signaling pathway

C Wang, Y Wang, X Chang, X Ba, N Hu… - Cancer Management …, 2020 - Taylor & Francis
Background Tumor-derived exosomes are messengers that participate in tumor progression.
Fibroblasts are associated with the metastasis of cancer depending on their cellular …

Exosome-mediated miR-222 transferring: An insight into NF-κB-mediated breast cancer metastasis

J Ding, Z Xu, Y Zhang, C Tan, W Hu, M Wang… - Experimental cell …, 2018 - Elsevier
The subtypes of distant-organ metastasis led to treatment failure and poor prognosis are
major obstacles in the management of patients with advanced breast cancer (BCa) …

[HTML][HTML] Exosomal miR-500a-5p derived from cancer-associated fibroblasts promotes breast cancer cell proliferation and metastasis through targeting USP28

B Chen, Y Sang, X Song, D Zhang, L Wang, W Zhao… - Theranostics, 2021 - ncbi.nlm.nih.gov
The tumor microenvironment contributes to tumor progression and metastasis. Cancer-
associated fibroblasts (CAFs) form a major cellular component of the tumor …

Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer

R Singh, R Pochampally, K Watabe, Z Lu, YY Mo - Molecular cancer, 2014 - Springer
Introduction Exosomes are 30-100 nm membrane vesicles of endocytic origin, mediating
diverse biological functions including tumor cell invasion, cell-cell communication and …