Conclusions: Our findings demonstrated that the GABAergic system suffers significant
remodeling in the brains of AD patients, yet it is to be determined if this is as a consequence …

Glutamatergic and cholinergic dysfunction are well‐attested features of Alzheimer's disease
(AD), progressing with other pathological indices of the disorder and exacerbating neuronal …

γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the vertebrate brain.
In the past, there has been a major research drive focused on the dysfunction of the …

Gamma‐aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central
nervous system. GABA type A receptors (GABAAR s) are severely affected in Alzheimer's …

Despite their possible causative role, targeting amyloidosis, tau phosphorylation,
acetylcholine esterase, glutamate, oxidative stress and mitochondrial metabolism have not …

Alzheimer's disease (AD) is characterized by selective vulnerability of specific neuronal
populations within particular brain regions. For example, hippocampal glutamatergic cell …

Our work on the role of glutamate in Alzheimer's disease (AD)-related neuronal vulnerability
and death provided significant insight into the potential contribution of the γ-aminobutyric …

In this article we present a comprehensive review of relevant research and reports on the
GABAA receptor in the aged and Alzheimer's disease (AD) brain. In comparison to …

We employed in situ hybridization and quantitative densitometry techniques to examine
hippocampal mRNA expression of GABAA receptor subunits α1 and α5 in human subjects …

GABA is the primary inhibitory neurotransmitter in the nervous system. GABAA receptors
(GABAARs) are pentameric ionotropic channels. Subunit composition of the receptors is …