Activation of adenosine A2A receptor signaling regulates the expression of cytokines associated with immunologic dysfunction in BTBR T+ Itpr3tf/J mice
Autism spectrum disorder (ASD) is neurodevelopmental disorders characterized by
stereotypical repetitive behavior, impaired social interaction, and deficits in communication …
stereotypical repetitive behavior, impaired social interaction, and deficits in communication …
Adenosine A2A receptor modulates neuroimmune function through Th17/retinoid-related orphan receptor gamma t (RORγt) signaling in a BTBR T+ Itpr3tf/J mouse …
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by abnormal social interactions, repetitive behaviors that impair social communication, and …
by abnormal social interactions, repetitive behaviors that impair social communication, and …
Adenosine A2A receptor signaling affects IL-21/IL-22 cytokines and GATA3/T-bet transcription factor expression in CD4+ T cells from a BTBR T+ Itpr3tf/J mouse model …
Autism is a complex heterogeneous neurodevelopmental disorder; previous studies have
identified altered immune responses among individuals diagnosed with autism. An …
identified altered immune responses among individuals diagnosed with autism. An …
Toll-like receptors, NF-κB, and IL-27 mediate adenosine A2A receptor signaling in BTBR T+ Itpr3tf/J mice
Autism is a predominant neurodevelopmental disorder characterized by impaired
communication, social deficits, and repetitive behaviors. Recent research has proposed that …
communication, social deficits, and repetitive behaviors. Recent research has proposed that …
Immune Alterations in CD8+ T Cells Are Associated with Neuronal CC and CXC Chemokine Receptor Regulation Through Adenosine A2A Receptor Signaling in a BTBR T+ …
Associative studies on a range of neurodevelopmental disorders have identified
relationships between behavioral deficits and immune system function. The BTBR T+ Itpr3 …
relationships between behavioral deficits and immune system function. The BTBR T+ Itpr3 …
[HTML][HTML] Blocking A2B adenosine receptor alleviates pathogenesis of experimental autoimmune encephalomyelitis via inhibition of IL-6 production and Th17 …
W Wei, C Du, J Lv, G Zhao, Z Li, Z Wu… - The Journal of …, 2013 - journals.aai.org
Adenosine is a key endogenous signaling molecule that regulates immune responses. A 2B
adenosine receptor (AR) is a relatively low-affinity receptor for adenosine, and the activation …
adenosine receptor (AR) is a relatively low-affinity receptor for adenosine, and the activation …
A2B adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway
The hallmark of neuroinflammation is the activation of microglia, the immunocompetent cells
of the CNS, releasing a number of proinflammatory mediators implicated in the …
of the CNS, releasing a number of proinflammatory mediators implicated in the …
Short‐term TNF‐Alpha treatment induced A2B adenosine receptor desensitization in human astroglial cells
ML Trincavelli, I Tonazzini, M Montali… - Journal of cellular …, 2008 - Wiley Online Library
Long‐term glial cell treatment with the proinflammatory cytokine TNF‐alpha has been
demonstrated to increase the functional responsiveness of A2B adenosine receptors (A2B …
demonstrated to increase the functional responsiveness of A2B adenosine receptors (A2B …
[HTML][HTML] 5-Aminoisoquinolinone, a PARP-1 inhibitor, ameliorates immune abnormalities through upregulation of anti-inflammatory and downregulation of inflammatory …
Autism spectrum disorder (ASD) covers a range of neurodevelopmental disorders involving
impairments in communication and repetitive and stereotyped patterns of behavior and …
impairments in communication and repetitive and stereotyped patterns of behavior and …
5-aminoisoquinolinone attenuates social behavior deficits and immune abnormalities in the BTBR T+ Itpr3tf/J mouse model for autism
Autism spectrum disorder (ASD) is diagnosed by core symptoms including impaired social
communication and the presence of repetitive and stereotypical behaviors. There is also …
communication and the presence of repetitive and stereotypical behaviors. There is also …