Tumor treating fields: at the crossroads between physics and biology for cancer treatment

FA Carrieri, C Smack, I Siddiqui, LR Kleinberg… - Frontiers in …, 2020 - frontiersin.org
Despite extraordinary advances that have been achieved in the last few decades, cancer
continues to represent a leading cause of mortality worldwide. Lethal cancer types ultimately …

Tumor-treating fields: a fourth modality in cancer treatment

EJ Mun, HM Babiker, U Weinberg, ED Kirson… - Clinical Cancer …, 2018 - AACR
Despite major advances in therapy, cancer continues to be a leading cause of mortality. In
addition, toxicities of traditional therapies pose a significant challenge to tolerability and …

Tumor Treating Fields (TTFields) hinder cancer cell motility through regulation of microtubule and actin dynamics

T Voloshin, RS Schneiderman, A Volodin, RR Shamir… - Cancers, 2020 - mdpi.com
Simple Summary Tumor Treating Fields (TTFields), encompassing alternating electric fields
within the intermediate frequency range, is an anticancer treatment delivered to the tumor …

Tumor treating fields: a comprehensive overview of the underlying molecular mechanism

P Hong, N Kudulaiti, S Wu, J Nie… - Expert review of …, 2022 - Taylor & Francis
Introduction As a novel treatment modality, tumor treating fields (TTFields) exert low-
intensity, medium-frequency electric fields on tumor cells. TTFields' effectiveness and safety …

Tumor treating fields: a new frontier in cancer therapy

AM Davies, U Weinberg, Y Palti - … of the New York Academy of …, 2013 - Wiley Online Library
Tumor treating fields (TTFields) is a noninvasive, regional antimitotic treatment modality that
has been approved for the treatment of recurrent glioblastoma by the US FDA and has a CE …

Tumor treating fields: concept, evidence and future

M Pless, U Weinberg - Expert opinion on investigational drugs, 2011 - Taylor & Francis
Introduction: Local control is fundamental, both for the curative as well as the palliative
treatment of cancer. Tumor treating fields (TTFields) are low intensity (1–2 V/cm) …

In Vivo Safety of Tumor Treating Fields (TTFields) Applied to the Torso

R Blatt, S Davidi, M Munster, A Shteingauz… - Frontiers in …, 2021 - frontiersin.org
Background Tumor Treating Fields (TTFields) therapy is a non-invasive, loco-regional, anti-
mitotic treatment modality that targets rapidly dividing cancerous cells, utilizing low intensity …

Tumor-Treating Fields: A fourth modality in cancer treatment, new practice updates

R Arvind, SR Chandana, MJ Borad… - Critical Reviews in …, 2021 - Elsevier
Although major innovations in treatment are advancing, cancer persists as one of the
leading causes of mortality. With the rising incidence of cancer and as we treat them …

An overview of potential novel mechanisms of action underlying Tumor Treating Fields-induced cancer cell death and their clinical implications

NK Karanam, MD Story - International journal of radiation biology, 2021 - Taylor & Francis
Traditional cancer therapy choices for clinicians are surgery, chemotherapy, radiation and
immune therapy which are used either standalone therapies or in various combinations …

Integration of tumor‐treating fields into the multidisciplinary management of patients with solid malignancies

Y Wang, M Pandey, MT Ballo - The Oncologist, 2019 - academic.oup.com
Tumor‐treating fields (TTFields) are a noninvasive antimitotic cancer treatment consisting of
low‐intensity alternating electric fields delivered to the tumor or tumor bed via externally …