Acupuncture alleviates CUMS‐induced depression‐like behaviors by restoring prefrontal cortex neuroplasticity

P Li, W Huang, Y Chen, MS Aslam, W Cheng… - Neural …, 2023 - Wiley Online Library
Purpose. To explore the therapeutic efficiency of acupuncture and the related molecular
mechanism of neural plasticity in depression. Methods. Chronic unpredictable mild stress …

Mechanisms underlying the antidepressant response of acupuncture via PKA/CREB signaling pathway

H Jiang, X Zhang, Y Wang, H Zhang, J Li… - Neural …, 2017 - Wiley Online Library
Protein kinase A (PKA)/cAMP response element‐binding (CREB) protein signaling pathway,
contributing to impaired neurogenesis parallel to depressive‐like behaviors, has been …

Effects of acupuncture on chronic stress-induced depression-like behavior and its central neural mechanism

MJ Lee, JS Ryu, SK Won, U Namgung, J Jung… - Frontiers in …, 2019 - frontiersin.org
Depression is a serious psychiatric disorder with an enormous socioeconomic burden, and it
is commonly comorbid with pain, chronic fatigue, or other inflammatory diseases. Recent …

Acupuncture relieves stress-induced depressive behavior by reducing oxidative stress and neuroapoptosis in rats

WJ Cheng, P Li, WY Huang, Y Huang… - Frontiers in Behavioral …, 2022 - frontiersin.org
Oxidative stress is closely related to the occurrence of depression. Acupuncture has been
proved to be an effective method for treating depression. In order to explore the mechanism …

Acupuncture alleviated depressive-like behavior by down-regulating nf-κb, inos and no levels in prefrontal cortex of depression rats

R Pu, RH Shao, J Lu, SY Jin, Y Tu - Zhen ci yan jiu= Acupuncture …, 2018 - europepmc.org
Objective To observe the effect of acupuncture intervention on depressive-like behavior and
nuclear factor-κB (NF-κB), inducible nitric oxide synthase (iNOS) and nitric oxide (NO) levels …

Acupuncture ameliorates inflammatory response in a chronic unpredictable stress rat model of depression

J Lu, RH Shao, SY Jin, L Hu, Y Tu, JY Guo - Brain Research Bulletin, 2017 - Elsevier
Depression is one of the most common psychiatric disorders. Chronic inflammatory
response has been viewed as a key factor in depression. Acupuncture in Chinese medicine …

The rapid antidepressant effect of acupuncture on two animal models of depression by inhibiting M1-Ach receptors regulates synaptic plasticity in the prefrontal cortex

B Ning, Z Wang, J He, Q Wu, Q Deng, Q Yang, J Gao… - Brain Research, 2024 - Elsevier
Background It is unclear whether acupuncture has a rapid antidepressant effect and what is
the main mechanism. Methods In this study, forced swimming stress test (FST) in mice were …

Acupuncture treatment for social defeat stress

J Kawanokuchi, K Takagi, N Tanahashi… - Frontiers in Behavioral …, 2021 - frontiersin.org
Depression is a mood disorder characterized by disordered affect, thoughts, cognition, and
behavior. Antidepressant therapy is often the primary treatment for depression. However …

[HTML][HTML] Electroacupuncture alleviates the symptom of depression in mice by regulating the cGAS-STING-NLRP3 signaling

S Chen, J Li, L Yan, X Zhang, J Huang… - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Purpose: To investigate the therapeutic effect of electroacupuncture (EA) on chronic and
unpredictable mild stress (CUMS)-induced depression in mice and the underlying …

Potential antiinflammatory effects of acupuncture in a chronic stress model of depression in rats

J Lu, RH Shao, L Hu, Y Tu, JY Guo - Neuroscience letters, 2016 - Elsevier
Accumulating evidence indicates that inflammation may contribute to the pathophysiology of
depression. Acupuncture in traditional Chinese medicine has been considered an effective …