Thymic stromal lymphopoietin is a critical mediator of IL‐13‐driven allergic inflammation

M Miyata, Y Nakamura, N Shimokawa… - European journal of …, 2009 - Wiley Online Library
Both thymic stromal lymphopoietin (TSLP) and IL‐13 are essential cytokines for the
development of allergic inflammation. However, a causal link between TSLP and IL‐13 has …

Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP

W Yao, Y Zhang, R Jabeen, ET Nguyen, DS Wilkes… - Immunity, 2013 - cell.com
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine important for the
initiation and development of T helper (Th2) cell-mediated allergic inflammation. In this …

Thymic stromal lymphopoietin, OX40‐ligand, and interleukin‐25 in allergic responses

YH Wang, YJ Liu - Clinical & Experimental Allergy, 2009 - Wiley Online Library
Allergic diseases are often triggered by environmental allergens that induce dominant type 2
immune responses, characterized by the infiltrated T‐helper type 2 (TH2) lymphocytes …

Thymic stromal lymphopoietin–induced human asthmatic airway epithelial cell proliferation through an IL-13–dependent pathway

A Semlali, E Jacques, L Koussih, AS Gounni… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Thymic stromal lymphopoietin (TSLP) plays a pivotal role in the initiation of
allergic airway inflammation. This cytokine is produced by several cell types, including …

Thymic stromal lymphopoietin and the pathophysiology of atopic disease

MM Miazgowicz, MB Headley, RP Larson… - Expert review of …, 2009 - Taylor & Francis
Thymic stromal lymphopoietin (TSLP) is an IL-7-related cytokine expressed predominantly
by barrier epithelial cells. TSLP is a potent activator of several cell types, including myeloid …

Thymic stromal lymphopoietin: master switch for allergic inflammation

YJ Liu - The Journal of experimental medicine, 2006 - rupress.org
Thymic stromal lymphopoietin (TSLP) is an interleukin (IL) 7–like cytokine that triggers
dendritic cell–mediated T helper (Th) 2 inflammatory responses. TSLP is highly expressed …

Cytokine pathways in allergic disease

CMM Williams, S Rahman, C Hubeau… - Toxicologic …, 2012 - journals.sagepub.com
Cytokines are critical in allergic intercellular communication networks, and they contribute to
disease pathology through the recruitment and activation of pro-inflammatory leukocytes …

Murine allergic rhinitis and nasal T h2 activation are mediated via TSLP- and IL-33-signaling pathways

S Akasaki, K Matsushita, Y Kato… - International …, 2016 - academic.oup.com
Thymic stromal lymphopoietin (TSLP) and IL-33 are epithelium-derived proallergic cytokines
that contribute to allergic diseases. Although the involvement of TSLP in allergic rhinitis (AR) …

Human thymic stromal lymphopoietin: a novel epithelial cell-derived cytokine and a potential key player in the induction of allergic inflammation

V Soumelis, YJ Liu - Springer seminars in immunopathology, 2004 - Springer
Allergy is the result of a complex immune cascade leading to the dysregulated production of
Th2 cytokines, the generation of allergen-specific IgE-producing B cells and the subsequent …

Regulation of interleukin‐33 and thymic stromal lymphopoietin in human nasal fibroblasts by proinflammatory cytokines

K Nomura, T Kojima, J Fuchimoto, K Obata… - The …, 2012 - Wiley Online Library
Abstract Objectives/Hypothesis: Epithelial‐derived interleukin (IL)‐33 and thymic stromal
lymphopoietin (TSLP) are critical regulators of innate and adaptive immune responses …