Norboldine improves cognitive impairment and pathological features in Alzheimer's disease by activating AMPK/GSK3β/Nrf2 signaling pathway

Y Zeng, L Xiong, H Tang, L Chen, Q Yu, L Li… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Lindera aggregata (Sims) Kosterm is a common
traditional herb that has multiple bioactivities. Radix Linderae (LR), the dry roots of Lindera …

Neuroprotective assessment of betaine against copper oxide nanoparticle-induced neurotoxicity in the brains of albino rats: a histopathological, neurochemical, and …

AR Hashim, DW Bashir, E Rashad… - ACS Chemical …, 2024 - ACS Publications
Copper oxide nanoparticles (CuO-NPs) are commonly used metal oxides. Betaine
possesses antioxidant and neuroprotective activities. The current study aimed to investigate …

[HTML][HTML] Comprehensive evaluation of microRNA expression profiling reveals the neural signaling specific cytotoxicity of superparamagnetic iron oxide nanoparticles …

B Sun, R Liu, N Ye, ZD Xiao - PLoS One, 2015 - journals.plos.org
Though nanomaterials are considered as drug carriers or imaging reagents targeting the
central nervous system their cytotoxicity effect on neuronal cells has not been well studied …

Potential of nobiletin against Alzheimer's disease through inhibiting neuroinflammation

W Chai, J Zhang, Z Xiang, H Zhang, Z Mei, H Nie… - Metabolic brain …, 2022 - Springer
Objective This study aimed to explore the mechanism of Nobiletin attenuating Alzheimer's
disease (AD) by inhibiting neuroinflammation. Methods The expression of inflammatory …

[HTML][HTML] Astilbin exerts a neuroprotective effect by upregulating the signaling of nuclear NF-E2-related factor 2 in vitro

C Guo, Y Yin, Z Ma, F Xu, S Wang - Heliyon, 2024 - cell.com
Objective The present study aims to evaluate the impact of Astilbin (AST) on cortical neuron
survival in vitro under conditions of oxygen-glucose deprivation and reoxygenation (OGD/R) …

Neuroprotection impact of biochanin A against pentylenetetrazol-kindled mice: targeting NLRP3 inflammasome/TXNIP pathway and autophagy modulation

RM El-Sayed, MN Fawzy, HF Zaki… - International …, 2023 - Elsevier
Recurrent seizures characterize epilepsy, a complicated and multifaceted neurological
disease. Several neurological alterations, such as cell death and the growth of gorse fibers …

Ginsenoside Rf inhibits human tau proteotoxicity and causes specific LncRNA, miRNA and mRNA expression changes in Caenorhabditis elegans model of tauopathy

S Zhang, H Wang, J Wang, W Jin, X Yan… - European journal of …, 2022 - Elsevier
Under pathological conditions, human tau (htau) hyperphosphorylation promotes formation
of proteotoxic intracellular amyloid aggregates that may underlie neurodegenerative …

Neuroprotective and Anti-Apoptotic Propensity of Bacopa monniera Extract Against Sodium Nitroprusside Induced Activation of iNOS, Heat Shock Proteins and …

MD Pandareesh, T Anand - Neurochemical research, 2014 - Springer
Sodium nitroprusside (SNP) is a widely used nitric oxide (NO) donor, known to exert nitrative
stress by up-regulation of inducible nitric oxide synthase (iNOS). Nω-nitro-l-arginine-methyl …

[HTML][HTML] Salvianolic acid B attenuates toxin-induced neuronal damage via Nrf2-dependent glial cells-mediated protective activity in Parkinson's disease models

J Zhou, XD Qu, ZY Li, Q Liu, YH Ma, JJ He - PloS one, 2014 - journals.plos.org
Salvianolic acid B (SalB), a bioactive compound isolated from the plant-derived medicinal
herb Danshen, has been shown to exert various anti-oxidative and anti-inflammatory …

[HTML][HTML] Nobiletin exhibits neuroprotective effects against mitochondrial complex I inhibition via regulating apoptotic signaling

K Amarsanaa, HJ Kim, EA Ko, J Jo… - Experimental …, 2021 - ncbi.nlm.nih.gov
Nobiletin, a polymethoxylated flavonoid found in citrus, has been studied because of its
modulatory functions in cellular signaling cascades, and effects to prevent mitochondrial …