Sepsis remains a serious cause of morbidity and mortality, and the pathophysiology of the
disease is not clear. The definition of the clinical manifestations of sepsis is ever evolving …

Sepsis is defined as “a life‐threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection.” At present, sepsis continues to …

This book is designed to provide a comprehensive and state-of-the-art resource for
clinicians who care for patients with sepsis and research scientist alike,. Patients with severe …

Over the last 100 years, huge advances have been made in the field of sepsis in terms of
pathophysiology, epidemiology, diagnosis, monitoring, and therapeutics. Here, we offer our …

Sepsis can be seen as a PRR-mediated dysregulation of the immune system following
pathogen invasion in which a careful balance between inflammatory and anti-inflammatory …

Sepsis secondary to bacterial infection remains a significant cause of morbidity and mortality
globally. Recent decades have seen the evolution of international collaborations to improve …

The underlying cause of sepsis is a dysregulated host response to infection, leading to
multiple organ failure. Identifying sepsis is crucial because of the associated …

Sepsis is a clinical syndrome encompassing physiologic and biological abnormalities
caused by a dysregulated host response to infection. Sepsis progression into septic shock is …

As of 2017, the World Health Organization has made the recognition, prevention, and
management of sepsis a global health priority. 1 Hippocrates considered the term a …

Sepsis, defined as an infection accompanied by inflammation, is a complex disease process
wherein the body's response to a pathogen is amplified far beyond the initial site of infection …