The pathogenic, diagnostic and therapeutic landscape of sepsis is no longer confined to the
intensive care unit: many patients from other portals of entry to care, both outside and within …

Multiple clinical trials of adjunctive therapy for sepsis and septic shock have been conducted
to neutralize bacterial components or to modulate host inflammatory responses to infection …

Sepsis is a common and lethal syndrome: although outcomes have improved, mortality
remains high. No specific anti-sepsis treatments exist; as such, management of patients …

Pathophysiologic basis of sepsis: Considerations for future... : Critical Care Medicine
Pathophysiologic basis of sepsis: Considerations for future strategies of intervention : Critical …

Sepsis is a life-threatening condition and a significant cause of preventable morbidity and
mortality globally. Among the leading causative agents of sepsis are bacterial pathogens …

Sepsis remains a critical problem with significant morbidity and mortality even in the modern
era of critical care management. Multiple derangements exist in sepsis involving several …

Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

Sepsis is a complex syndrome characterized by simultaneous activation of inflammation and
coagulation in response to microbial insult. These events manifest as systemic inflammatory …

The understanding of severe sepsis and septic shock could be on the verge of a
breakthrough, in view of research overturning the long-held belief that the conditions are …

Sepsis remains a major cause of morbidity and mortality worldwide, with increased burden
in low-and middle-resource settings. The role of the inflammatory response in the …