Biochemical changes associated with selective neuronal death following short-term cerebral ischaemia

NR Sims, E Zaidan - The International Journal of Biochemistry & Cell …, 1995 - Elsevier
A brief interruption of blood flow to the brain results in the selective loss of specific
subpopulations of neurons. Important advances have been made in recent years in defining …

Energy metabolism and selective neuronal vulnerability following global cerebral ischemia

NR Sims - Neurochemical research, 1992 - Springer
A short period of global ischemia results in the death of selected subpopulations of neurons.
Some advances have been made in understanding events which might contribute to the …

Calcium, energy metabolism and the development of selective neuronal loss following short-term cerebral ischemia

NR Sims - Metabolic brain disease, 1995 - Springer
Short-term cerebral ischemia results in the delayed loss of specific neuronal subpopulations.
This review discusses changes in energy metabolism and Ca 2+ distribution during …

The pathophysiology of brain ischemia

ME Raichle - Annals of Neurology: Official Journal of the …, 1983 - Wiley Online Library
Brain ischemia due to a critical reduction in cerebral blood flow is a well recognized and
common cause of irreversible brain damage. The observation that brain cells are more …

Physiopathology of cerebral ischemia.

JH Garcia, ML Anderson - Critical reviews in neurobiology, 1989 - europepmc.org
In spite of significant advances made in the technology to image the intracranial contents
and to measure the metabolic activity of discrete brain sites, the factor (s) responsible for the …

Histopathologic clues to the pathways of neuronal death following ischemia/hypoxia

WI ROSENBLUM - Journal of neurotrauma, 1997 - liebertpub.com
This review describes histopathologic observations made with both light and electron
microscopy using both conventional staining techniques and histochemistry. Several …

Mechanisms of secondary brain damage in global and focal ischemia: a speculative synthesis

BOK SIESJÖ, KENI KATSURA, QI Zhao… - Journal of …, 1995 - liebertpub.com
The objective of this article is to amalgamate previous results into a speculative synthesis
that sheds light on the causes of secondary brain damage following either global/forebrain …

Pathophysiology of cerebral ischemia

RL Macdonald, M Stoodley - Neurologia medico-chirurgica, 1998 - jstage.jst.go.jp
The purpose of this manuscript is to briefly review the pathophysiology of cerebral ischemia.
Ischemic thresholds are well-defined in lower animals. The concept of the ischemic …

Ischemic cell death: dynamics of delayed secondary energy failure during reperfusion following focal ischemia

WD Lust, C Taylor, S Pundik, WR Selman… - Metabolic brain …, 2002 - Springer
Reperfusion injury is believed to contribute to the pathophysiology of ischemic cell death,
but the precipitating factors have yet to be completely elucidated. The goal of this study was …

The role of postischemic recirculation in the development of ischemic neuronal injury following complete cerebral ischemia

LW Jenkins, JT Povlishock, W Lewelt, JD Miller… - Acta …, 1981 - Springer
The neuronal response to complete cerebral ischemia (CCI) of 5–15 min duration was
evaluated at the light and electron microscopic level subsequent to postischemic …