Abstract 17β-estradiol, acting through estrogen receptors α and β, plays a fundamental role
in the regulation of Fallopian tube cell homeostasis and in the modulation of normal tubal …

Ectopic pregnancy is defined as a pregnancy implanted outside the uterus, and> 98%
implant in the Fallopian tube. It has a major clinical and socioeconomic impact worldwide …

The physiological responses of the rodent uterus to acute estrogen (E) dosing can be
divided into early and late events. Examples of early responses include increased RNA …

Knowledge surrounding estrogen and estrogen receptor biology continues to evolve, and
the diversity of their actions and complexity of their mechanisms are becoming increasingly …

Estradiol-17β (E2) stimulates uterine and vaginal epithelial proliferation in vivo [1]. E2 also
plays a critical role in other aspects of uterine and vaginal growth and adult function, and it is …

Estrogens exert their activity through estrogen receptor alpha (ERalpha) to stimulate
hypertrophy and hyperplasia in the uterus. A uterine epithelial ERalpha conditional knockout …

Estrogens have traditionally been considered female hormones. Nevertheless, the presence
of estrogen in males has been known for over 90 years. Initial studies suggested that …

Estrogen receptors (ERs) are members of the nuclear receptor superfamily and are involved
in regulation of fallopian tube functions (ie, enhancement of protein secretion, formation of …

The harmonized actions of ovarian E2 and progesterone (P4) regulate the proliferation and
differentiation of uterine cells in a spatiotemporal manner. Imbalances between these …

Estrogen signaling through the main estrogen receptor, estrogen receptor 1 (ESR1; also
known as ERα), is essential for normal female and male reproductive function. Historically …