Integrated bioinformatics and network pharmacology to identify the therapeutic target and molecular mechanisms of Huangqin decoction on ulcerative Colitis

Y Wu, X Liu, G Li - Scientific reports, 2022 - nature.com
Huangqin decoction (HQD) is a Traditional Chinese Medicine formula for ulcerative colitis.
However, the pharmacology and molecular mechanism of HQD on ulcerative colitis is still …

Network pharmacology and molecular docking analysis on molecular mechanism of Qingzi Zhitong decoction in the treatment of ulcerative colitis

X Shou, Y Wang, X Zhang, Y Zhang, Y Yang… - Frontiers in …, 2022 - frontiersin.org
Ulcerative colitis (UC) is a disease with complex pathological mechanisms. We explored the
potential molecular mechanisms behind the therapeutic functions of Qingzi Zhitong …

Based on network pharmacology to explore the molecular targets and mechanisms of Gegen Qinlian decoction for the treatment of ulcerative colitis

M Wei, H Li, Q Li, Y Qiao, Q Ma, R Xie… - BioMed Research …, 2020 - Wiley Online Library
Background. Gegen Qinlian (GGQL) decoction is a common Chinese herbal compound for
the treatment of ulcerative colitis (UC). In this study, we aimed to identify its molecular target …

Uncovering the mechanism of Ge-Gen-Qin-Lian decoction for treating ulcerative colitis based on network pharmacology and molecular docking verification

L Xu, J Zhang, Y Wang, Z Zhang, F Wang… - Bioscience …, 2021 - portlandpress.com
Abstract Background: Ge-Gen-Qin-Lian Decoction (GGQLD), a traditional Chinese medicine
(TCM) formula, has been widely used for ulcerative colitis (UC) in China, but the …

In silico and in vivo studies on the mechanisms of Chinese medicine formula (gegen qinlian decoction) in the treatment of ulcerative colitis

X Liu, Y Fan, L Du, Z Mei, Y Fu - Frontiers in Pharmacology, 2021 - frontiersin.org
Ulcerative colitis (UC) is a chronic inflammatory bowel disease, and Gegen Qinlian
Decoction (GQD), a Chinese botanical formula, has exhibited beneficial efficacy against UC …

Network pharmacology prediction and molecular docking-based strategy to discover the potential pharmacological mechanism of Huai Hua San against ulcerative …

J Liu, J Liu, X Tong, W Peng, S Wei, T Sun… - Drug Design …, 2021 - Taylor & Francis
Background Huai Hua San (HHS), a famous Traditional Chinese Medicine (TCM) formula,
has been widely applied in treating ulcerative colitis (UC). However, the interaction of …

Revealing the mechanism of “Huai Hua San” in the treatment of ulcerative colitis based on network pharmacology and experimental study

P Chen, C Yuan, Z Hong, Y Zhang, X Ke, B Yu… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance “Huai Hua San”(HHS) is one of the first hundred
ancient classic prescriptions drugs, which is commonly used to treat hemorrhoids, colitis …

Yiyi Fuzi Baijiang Powder Alleviates Dextran Sulfate Sodium‐Induced Ulcerative Colitis in Rats via Inhibiting the TLR4/NF‐κB/NLRP3 Inflammasome Signaling …

J Yang, L Miao, Y Xue, X Wang - Oxidative Medicine and …, 2023 - Wiley Online Library
Ulcerative colitis (UC) is a chronic non‐specific inflammatory disease of the intestine, which
is prone to recurrence and difficult to cure. Yiyi Fuzi Baijiang powder (YFBP), as a classic …

[HTML][HTML] Dendrobium huoshanense in the treatment of ulcerative colitis: Network pharmacology and experimental validation

L Yao, J Fang, J Zhao, J Yu, X Zhang, W Chen… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Dendrobium huoshanense CZ Tang et SJ Cheng (DH) is a
traditional medicinal herb with a long history of medicinal use. DH has been recorded as …

Mechanisms of indigo naturalis on treating ulcerative colitis explored by GEO gene chips combined with network pharmacology and molecular docking

S Gu, Y Xue, Y Gao, S Shen, Y Zhang, K Chen, S Xue… - Scientific reports, 2020 - nature.com
Oral administration of indigo naturalis (IN) can induce remission in ulcerative colitis (UC);
however, the underlying mechanism remains unknown. The main active components and …