Background Cardiac involvement is a major determinant of prognosis in type 1 myotonic
dystrophy (DM1), but limited information is available about myocardial remodeling and …

Aims Heart disease is a major determinant of prognosis in type 1 myotonic dystrophy (DM1),
second only to respiratory complications. Cardiac imaging, possibly including cardiac …

Background Myotonic dystrophy type 1 (MD1) is a neuromuscular disorder with potential
involvement of the heart and increased risk of sudden death. Considering the importance of …

Methods: In total, 38 patients with DM1, asymptomatic for cardiac disease, were
prospectively evaluated with clinical history, examination, genetic testing, transthoracic …

Background—Myotonic dystrophy type 2 (DM2) is a genetic disorder characterized by
skeletal muscle symptoms, metabolic changes, and cardiac involvement. Histopathologic …

Background Cardiac involvement represents a major cause of morbidity and mortality in
patients with myotonic dystrophy type 1 (DM1) and prevention of sudden cardiac death …

BACKGROUND: Myotonic dystrophy type 1 (DM1) is a neurological disorder with known
cardiac involvement, including conduction disturbances, arrhythmias, and ventricular …

Background Frequency and severity of cardiac involvement in DM2 are still controversial.
The aims of our study were to determine the frequency and progression of cardiac and …

Background Myotonic dystrophies (DM) are multi-systemic diseases characterized by
muscle weakness and myotonia. Despite a growing appreciation for the cardiovascular …

Objective Cardiac disease accounts for a large burden of premature mortality and morbidity
in patients with type 1 myotonic dystrophy (MD). However, little is known about structural …