Reversal by quercetin of corticotrophin releasing factor induced anxiety-and depression-like effect in mice

P Bhutada, Y Mundhada, K Bansod, A Ubgade… - Progress in Neuro …, 2010 - Elsevier
Quercetin is a bioflavonoid reported to produce variety of behavioral effects like anxiolytic,
antidepressant, etc. Recent gathering evidences indicated that quercetin attenuates stress …

Suppressive effect of quercetin on acute stress-induced hypothalamic-pituitary-adrenal axis response in Wistar rats

K Kawabata, Y Kawai, J Terao - The Journal of nutritional biochemistry, 2010 - Elsevier
The flavonoid quercetin is considered to have beneficial effects on human health. We
recently have shown that quercetin-enriched foods reduced the duration of immobility time in …

Resveratrol ameliorates depressive-like behavior in repeated corticosterone-induced depression in mice

SH Ali, RM Madhana, KV Athira, ER Kasala… - Steroids, 2015 - Elsevier
A mouse model of depression has been recently developed by exogenous corticosterone
(CORT) administration, which has shown to mimic HPA-axis induced depression-like state in …

Role of quercetin in depressive-like behaviors: Findings from animal models

S Silvestro, P Bramanti, E Mazzon - Applied Sciences, 2021 - mdpi.com
Depressive-like behavior is a highly prevalent worldwide neuropsychiatric disorder that
owns a complex pathophysiologic mechanism. The available pharmacotherapy is ineffective …

[PDF][PDF] Anxiolytic effects of quercetin: Involvement of GABAergic system

JW Jung, S Lee - Journal of Life Science, 2014 - researchgate.net
The present experiment investigated putative anxiolytic-like effects of quercetin using an
elevated plus-maze (EPM) and hole-board apparatus test in mice. Quercetin is a flavonoid …

Serotonergically dependent antidepressant-like activity on behavior and stress axis responsivity of acacetin

WZ Xiao, WH Zhou, Q Ma, WG Cui, QY Mei… - Pharmacological …, 2019 - Elsevier
Acacetin, a natural flavonoid, possesses broad spectrum of pharmacological and
biochemical activities, such as neuroprotection, antinociception and inhibition of monoamine …

Quercetin alleviates chronic unpredictable mild stress-induced depressive-like behaviors by promoting adult hippocampal neurogenesis via FoxG1/CREB/BDNF …

ZX Ma, RY Zhang, WJ Rui, ZQ Wang, X Feng - Behavioural brain research, 2021 - Elsevier
Quercetin, a naturally occurring flavonoid, has been reported to exert antidepressant effects,
however, the underlying mechanisms are still uncertain. Recent studies have demonstrated …

Dietary quercetin attenuates depressive-like behaviors by inhibiting astrocyte reactivation in response to stress

J Zhang, L Ning, J Wang - Biochemical and Biophysical Research …, 2020 - Elsevier
The mechanisms underlying the antidepressant activity of quercetin are unknown. We
investigated the effect of a quercetin-enriched diet (2 g/kg and 0.5 g/kg doses) on chronic …

Resveratrol reverses the effects of chronic unpredictable mild stress on behavior, serum corticosterone levels and BDNF expression in rats

D Liu, K Xie, X Yang, J Gu, L Ge, X Wang… - Behavioural brain …, 2014 - Elsevier
Depression is one of the most common neuropsychiatric disorders and has been associated
with the neuroendocrine system and alterations in specific brain proteins. Resveratrol is a …

Quercetin reverses chronic unpredictable mild stress-induced depression-like behavior in vivo by involving nuclear factor-E2-related factor 2

Y Guan, J Wang, X Wu, L Song, Y Wang, M Gong, B Li - Brain Research, 2021 - Elsevier
Quercetin is a flavonoid compound rich in many natural plants with a wide range of
pharmacological effects and nutritional value. Although previous studies have initially shown …