RNA N6-methyladenosine modifications and its roles in Alzheimer's disease
R Zhang, Y Zhang, F Guo, S Li, H Cui - Frontiers in cellular …, 2022 - frontiersin.org
The importance of epitranscriptomics in regulating gene expression has received
widespread attention. Recently, RNA methylation modifications, particularly N6 …
widespread attention. Recently, RNA methylation modifications, particularly N6 …
m6A methylation: Critical roles in aging and neurological diseases
Y Fan, X Lv, Z Chen, Y Peng, M Zhang - Frontiers in Molecular …, 2023 - frontiersin.org
N6-methyladenosine (m6A) is the most abundant internal RNA modification in eukaryotic
cells, which participates in the functional regulation of various biological processes. It …
cells, which participates in the functional regulation of various biological processes. It …
Abnormality of m6A mRNA methylation is involved in Alzheimer's disease
M Han, Z Liu, Y Xu, X Liu, D Wang, F Li… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD), the most common form of dementia, is highly prevalent in older
adults. The main clinical feature is the progressive decline of memory function, which …
adults. The main clinical feature is the progressive decline of memory function, which …
Dynamic N6-methyladenosine RNA methylation in brain and diseases
N6-methyladenosine (m6A) is a dynamic RNA modification that regulates various aspects of
RNA metabolism and has been implicated in many biological processes and transitions …
RNA metabolism and has been implicated in many biological processes and transitions …
The potential role of m6A RNA methylation in the aging process and aging-associated diseases
J Sun, B Cheng, Y Su, M Li, S Ma, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
N6-methyladenosine (m6A) is the most common and conserved internal eukaryotic mRNA
modification. m6A modification is a dynamic and reversible post-transcriptional regulatory …
modification. m6A modification is a dynamic and reversible post-transcriptional regulatory …
In Search of a Function for the N6-Methyladenosine in Epitranscriptome, Autophagy and Neurodegenerative Diseases
N Suga, Y Ikeda, S Yoshikawa, K Taniguchi… - Neurology …, 2023 - mdpi.com
Changes in epitranscriptome with N6-methyladenine (m6A) modification could be involved
in the development of multiple diseases, which might be a prevalent modification of …
in the development of multiple diseases, which might be a prevalent modification of …
The landscape of m6A regulators in multiple brain regions of Alzheimer's disease
ZJ Liu, Q Xia, X Zhao, FF Zheng, JY Xiao, FL Ge… - Molecular …, 2023 - Springer
Alzheimer's disease research has been conducted for many years, yet no effective cure
methods have been found. N6-methyladenosine (m6A) RNA methylation, an essential post …
methods have been found. N6-methyladenosine (m6A) RNA methylation, an essential post …
N6-methyladenosine methylation of mRNA in cell senescence
L Zhang, J Xia - Cellular and Molecular Neurobiology, 2023 - Springer
Cell senescence is the growth arrest caused by the accumulation of irreparable cell
damage, which is involved in physiological and pathological processes and regulated by the …
damage, which is involved in physiological and pathological processes and regulated by the …
METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer's disease through aberrant cell cycle events
Abstract Background N6-methyladenosine (m 6 A) modification of RNA influences
fundamental aspects of RNA metabolism and m 6 A dysregulation is implicated in various …
fundamental aspects of RNA metabolism and m 6 A dysregulation is implicated in various …
m6A RNA methylation in brain injury and neurodegenerative disease
J Deng, X Chen, A Chen, X Zheng - Frontiers in Neurology, 2022 - frontiersin.org
N6-methyladenosine (m6A), the most prevalent post-transcriptional RNA modification
throughout the eukaryotic transcriptome, participates in diverse biophysiological processes …
throughout the eukaryotic transcriptome, participates in diverse biophysiological processes …