A review of the current status of siRNA nanomedicines in the treatment of cancer
P Resnier, T Montier, V Mathieu, JP Benoit, C Passirani - Biomaterials, 2013 - Elsevier
RNA interference currently offers new opportunities for gene therapy by the specific
extinction of targeted gene (s) in cancer diseases. However, the main challenge for nucleic …
extinction of targeted gene (s) in cancer diseases. However, the main challenge for nucleic …
Advances in siRNA delivery approaches in cancer therapy: challenges and opportunities
Advancements in the clinical applications of small interfering RNA (siRNA) in cancer therapy
have opened up new possibilities for precision medicine. siRNAs, as powerful genetic tools …
have opened up new possibilities for precision medicine. siRNAs, as powerful genetic tools …
[HTML][HTML] Nano-formulated siRNA-based therapeutic approaches for cancer therapy
D Jain, SK Prajapati, A Jain, R Singhal - Nano Trends, 2023 - Elsevier
RNAi is a remarkable treatment strategy to knock down gene overexpression in a variety of
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …
Nonviral methods for siRNA delivery
K Gao, L Huang - Molecular pharmaceutics, 2009 - ACS Publications
RNA interference (RNAi) as a mechanism to selectively degrade mRNA (mRNA) expression
has emerged as a potential novel approach for drug target validation and the study of …
has emerged as a potential novel approach for drug target validation and the study of …
Advances in siRNA delivery in cancer therapy
A Singh, P Trivedi, NK Jain - Artificial cells, nanomedicine, and …, 2018 - Taylor & Francis
RNA interference (RNAi)-based therapeutic approaches are under vibrant scrutinisation to
seek cancer cure. siRNA suppress expression of the carcinogenic genes by targeting the …
seek cancer cure. siRNA suppress expression of the carcinogenic genes by targeting the …
Clinical advances of siRNA-based nanotherapeutics for cancer treatment
Cancer is associated with single or multiple gene defects. Recently, much research has
focused on incorporating genetic materials as one of the means to treat various types of …
focused on incorporating genetic materials as one of the means to treat various types of …
Nanoparticle‐mediated siRNA delivery systems for cancer therapy
The small interfering RNA (siRNA)‐based therapeutics have raised great attention since the
first RNA interference (RNAi)‐derived drug, patisiran, was approved by the US Food and …
first RNA interference (RNAi)‐derived drug, patisiran, was approved by the US Food and …
Recent advancements in the design of nanodelivery systems of siRNA for cancer therapy
RNA interference (RNAi) has increased the possibility of restoring RNA drug targets for
cancer treatment. Small interfering RNA (siRNA) is a promising therapeutic RNAi tool that …
cancer treatment. Small interfering RNA (siRNA) is a promising therapeutic RNAi tool that …
Safety profile of RNAi nanomedicines
SA Barros, JA Gollob - Advanced drug delivery reviews, 2012 - Elsevier
The emerging class of RNA interference (RNAi) therapeutics is a fundamentally novel
approach to treating human disease by enabling the pursuit of molecular targets considered …
approach to treating human disease by enabling the pursuit of molecular targets considered …
Tumor‐targeting multifunctional nanoparticles for siRNA delivery: Recent advances in cancer therapy
RNA interference (RNAi) is a naturally occurring regulatory process that controls
posttranscriptional gene expression. Small interfering RNA (siRNA), a common form of RNAi …
posttranscriptional gene expression. Small interfering RNA (siRNA), a common form of RNAi …