Quantitative iTRAQ-based proteomic identification of candidate biomarkers for diabetic nephropathy in plasma of type 1 diabetic patients

AJ Overgaard, TE Thingholm, MR Larsen, L Tarnow… - Clinical proteomics, 2010 - Springer
Introduction As part of a clinical proteomics programme focused on diabetes and its
complications, it was our goal to investigate the proteome of plasma in order to find …

Plasma proteome analysis of patients with type 1 diabetes with diabetic nephropathy

AJ Overgaard, HG Hansen, M Lajer, L Pedersen… - Proteome science, 2010 - Springer
Background As part of a clinical proteomics program focused on diabetes and its
complications we are looking for new and better protein biomarkers for diabetic …

iTRAQ plasma proteomics analysis for candidate biomarkers of type 2 incipient diabetic nephropathy

H Lu, S Deng, M Zheng, K Hu - Clinical Proteomics, 2019 - Springer
Background Diabetic nephropathy is the most frequent cause of end-stage renal disease
worldwide. Identification of biomarkers for diabetic nephropathy for early diagnosis may be …

Differential proteome profiling using iTRAQ in microalbuminuric and normoalbuminuric type 2 diabetic patients

J Jin, YH Ku, Y Kim, Y Kim, K Kim… - Journal of Diabetes …, 2012 - Wiley Online Library
Diabetic nephropathy (DN) is a long‐term complication of diabetes mellitus that leads to end‐
stage renal disease. Microalbuminuria is used for the early detection of diabetic renal …

A discovery-phase urine proteomics investigation in type 1 diabetes

A Soggiu, C Piras, L Bonizzi, HA Hussein, S Pisanu… - Acta …, 2012 - Springer
Diabetes is a chronic metabolic disease which can lead to serious health problems
particularly in and to the development of cardiovascular and renal complications. The aim of …

Urinary proteins detected using modern proteomics intervene in early type 2 diabetic kidney disease–a pilot study

A Golea-Secara, C Munteanu, M Sarbu… - Biomarkers in …, 2020 - Taylor & Francis
Aim: An advanced proteomics platform for protein biomarker discovery in diabetic chronic
kidney disease (DKD) was developed, validated and implemented. Materials & methods …

Proteomic identification of plasma biomarkers in type 2 diabetic nephropathy

PH Hung, YC Lu, YW Chen, HC Chou, PC Lyu… - Journal of Integrated …, 2011 - jiomics.com
Recent advances in quantitative proteomics have offered opportunities to discover plasma
proteins as biomarkers for tracking the progression and for understanding the molecular …

The discovery of biomarkers for type 2 diabetic nephropathy by serum proteome analysis

EH Cho, MR Kim, HJ Kim, DY Lee… - Proteomics–clinical …, 2007 - Wiley Online Library
Diabetic nephropathy (DN) is a serious kidney complication of diabetes, and constitutes the
leading cause of end‐stage renal disease. The earliest clinical evidence of DN is …

Proteome analysis of serum from type 2 diabetics with nephropathy

HJ Kim, EH Cho, JH Yoo, PK Kim, JS Shin… - Journal of proteome …, 2007 - ACS Publications
Diabetic nephropathy (DN) is a renal disease which develops as a consequence of diabetes
mellitus. Microalbuminuria is the earliest clinical sign of DN. There are no specific diagnostic …

Applying proteomics to diagnosis of diabetic kidney disease

RN Moresco, JAM De Carvalho - Expert review of proteomics, 2017 - Taylor & Francis
Diabetic kidney disease (DKD) is one the major complications of diabetes and has become
the most common cause of chronic kidney disease worldwide [1, 2]. The pathogenesis of …