Uptake inhibition of biogenic amines by newer antidepressant drugs: relevance to the dopamine hypothesis of depression
A Randrup, C Braestrup - Psychopharmacology, 1977 - Springer
The dopamine theory of depression was studied by assessing the effect of antidepressant
drugs on uptake of dopamine, noradrenaline, and serotonin in synaptosomes from rat brain …
drugs on uptake of dopamine, noradrenaline, and serotonin in synaptosomes from rat brain …
Dopamine and depression: a review of recent evidence. I. Empirical studies
P Willner - Brain Research Reviews, 1983 - Elsevier
This paper reviews evidence from human, predominantly clinical, studies, relevant to the
hypothesis that depression involves reduced levels of dopamine (DA) function. With the …
hypothesis that depression involves reduced levels of dopamine (DA) function. With the …
Dopamine autoreceptor subsensitivity: a mechanism common to the treatment of depression and the induction of amphetamine psychosis?
SM Antelman, LA Chiodo - Biological Psychiatry, 1981 - psycnet.apa.org
Reviews electrophysiological studies on animals, which indicate that a variety of
antidepressants (imipramine, amitriptyline, and iprindole), and also amphetamine, can …
antidepressants (imipramine, amitriptyline, and iprindole), and also amphetamine, can …
Relationship between dopaminergic and serotonergic neuronal activity in the frontal cortex and the action of typical and atypical antipsychotic drugs
J Ichikawa, HY Meltzer - European Archives of Psychiatry and Clinical …, 1999 - Springer
Abstract Clozapine, iloperidone, quetiapine, olanzapine, risperidone and ziprasidone
represent the new generation of antipsychotic drugs, successors to the typical antipsychotic …
represent the new generation of antipsychotic drugs, successors to the typical antipsychotic …
Dopamine and depression — Striatal dopamine D2 receptor SPECT before and after antidepressant therapy
D Ebert, T Loew, H Feistel, A Pirner - Psychopharmacology, 1996 - Springer
Ten unmedicated and ten medicated patients with major depression and ten controls were
investigated with IBZM-SPECT. The ten unmedicated patients were reinvestigated after …
investigated with IBZM-SPECT. The ten unmedicated patients were reinvestigated after …
The pharmacology of antidepressants at the synapse: focus on newer compounds.
E Richelson - The Journal of clinical psychiatry, 1994 - europepmc.org
This paper reviews the in vitro effects of antidepressants on blockade of uptake of
norepinephrine, serotonin, and dopamine at the synapse (rat synaptosomal preparations) …
norepinephrine, serotonin, and dopamine at the synapse (rat synaptosomal preparations) …
Interactions of antidepressants with neurotransmitter transporters and receptors and their clinical relevance
E Richelson - J Clin Psychiatry, 2003 - psychiatrist.com
This review discusses the pharmacology of antidepressants as it relates to their blockade of
human transporters for norepinephrine, serotonin, and dopamine, as well as their blockade …
human transporters for norepinephrine, serotonin, and dopamine, as well as their blockade …
Mianserin markedly and selectively increases extracellular dopamine in the prefrontal cortex as compared to the nucleus accumbens of the rat
The atypical antidepressant mianserin, administered at doses of 1, 5 and 10 mg/kg SC, dose-
dependently increased up to about 6 times extracellular dopamine in the medial prefrontal …
dependently increased up to about 6 times extracellular dopamine in the medial prefrontal …
Effects of antidepressant drugs on different receptors in the brain
H Hall, Ö Sven-Ove - European journal of pharmacology, 1981 - Elsevier
Radioligand receptor binding techniques were used to characterize the effects of different
structural types of antidepressant drugs on neurotransmitter receptors. The tricyclic …
structural types of antidepressant drugs on neurotransmitter receptors. The tricyclic …