Although the vital roles of structures containing sialic acid in biomolecular recognition are
well documented, limited information is available on how sialic acid structural modifications …

Sialic acid‐containing glycans play important roles in biology, but their synthesis by
standard chemical approaches is challenging. Enzymatic assembly is generally a better …

Sialic acids are a subset of nonulosonic acids, which are nine-carbon α-keto aldonic acids.
Natural existing sialic acid-containing structures are presented in different sialic acid forms …

A novel chemoenzymatic synthon strategy has been developed to construct a
comprehensive library of α2–3-and α2–6-linked sialosides containing 7-N-or 7, 9-di-N-acetyl …

Sialic acids are a family of α-keto acids with a 9-carbon backbone. They have been
predominantly found as terminal carbohydrate units on glycoproteins and glycolipids of …

The Siglec family of sialic acid-binding proteins are differentially expressed on white blood
cells of the immune system and represent an attractive class of targets for cell-directed …

Conspectus Sialic acids are fascinating negatively charged nine-carbon monosaccharides.
Sialic acid-containing glycans and glycoconjugates are structurally diverse, functionally …

Highlights•Chemical synthesis provided access to O-linked and S-linked oligosialic
acids.•Oxazolidinone-protected sialyl donors enable α-selective sialylation.•Enzymatic …

Four glycodendrons and a glycocluster were synthesized from carbohydrate building blocks
to form paucivalent (di-to tetravalent) structures of controlled scaffold architectures …

Sialidases, or neuraminidases, are enzymes that cleave terminal sialic acid (Sia) residues
from complex sialic acid‐containing structures. They have been found in many animals and …