Whole baker's yeast cells reduce t-butyl 6-chloro-3, 5-dioxohexanoate regioselectively to the
corresponding C5 hydroxy keto ester. While the (R)-alcohol was favored, the …

The stereoselectivity of baker's yeast in the reduction of ethyl 3-oxopentanoate was shifted
towards the corresponding (R)-hydroxy ester by sugar, heat treatment and allyl alcohol. The …

Microbial reductions of ketones hold great potential for the production of enantiopure
alcohols, as long as highly selective redox enzymes are not interfered with by competing …

1-Chloro-2, 4-alkanediones 1a–f prepared in one step were reduced using baker's yeast to
afford 1-chloro-2-hydroxy-4-alkanones 2a–f regioselectively in S 29% to R 58% ee. Use of a …

Several monoprotected dihydroxyacetone derivatives 4a–d and their acetates 5a–d were
prepared and subjected to biotransformation with baker's yeast. The simple chemical …

A stereoselective chemoenzymatic synthesis of all four stereoisomers of tert‐butyl 6‐chloro‐
3, 5‐dihydroxy‐hexanoate (6 a) is presented. The key step of the sequence is a highly regio …

A convenient approach to (S)-2-ethylhexan-1-ol mediated by baker’s yeast - ScienceDirect
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Although yeast reduction of α-diketones 1 affords a mixture of two α-hydroxy ketones and a
vic-diol, the use of methyl vinyl ketone as an enzyme inhibitor prevents the production of the …

The stereoselective reduction of ethyl 2-(benzamidomethyl)-3-oxobutanoate 1 using yeasts
was investigated among a restricted number (12) of yeasts. Kluyveromyces marxianusvar …

Six yeasts were studied for their ability to reduce ethyl 4-chloroacetoacetate (ethyl 4-chloro-3-
oxobutanoate) stereoselectively. Five species reduced the substrate to ethyl (S)-4-chloro-3 …