Background and Purpose—Although experimental data suggest that statin therapy may
improve neurological outcome after acute cerebral ischemia, the results from clinical studies …

Background and Purpose Statins have pleiotropic effects of potential neuroprotection.
However, because of lack of large randomized clinical trials, current guidelines do not …

Background and Purpose—Statins improve infarct volume and neurological outcome in
animal stroke models. We investigated the relationship between statin therapy and ischemic …

Background and Purpose—Multiple studies suggest that statin use before acute ischemic
stroke is associated with improved functional outcome. However, available evidence is …

Background and Purpose—Statins may be beneficial for patients with acute ischemic stroke.
We tested the hypothesis that patients pretreated with statins at the onset of stroke have less …

Background and Purpose—In primary and secondary prevention trials, statins have been
shown to reduce the risk of stroke. In addition to lipid lowering, statins have a number of …

Statins are effective cholesterol-lowering drugs for reducing the risks of mortality and
morbidity of cardiovascular diseases. Increasing evidence has shown that statin use is …

Abstract Background Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors)
have neuroprotective effects in experimental stroke models and are commonly prescribed in …

Background and Purpose—Statins reduce the risk for myocardial infarctions and stroke
which may in part depend on cholesterol-independent (pleiotropic) vasoprotective effects …

Background—In patients with ischemic stroke, data on the real-world effectiveness of statin
therapy for clinical and patient-centered outcomes are needed to better inform shared …