Assessing the clinical impact of approximations in analytical dose calculations for proton therapy

J Schuemann, D Giantsoudi, C Grassberger… - International Journal of …, 2015 - Elsevier
Purpose To assess the impact of approximations in current analytical dose calculation
methods (ADCs) on tumor control probability (TCP) in proton therapy. Methods Dose …

Comparison of linear energy transfer scoring techniques in Monte Carlo simulations of proton beams

DA Granville, GO Sawakuchi - Physics in Medicine & Biology, 2015 - iopscience.iop.org
Monte Carlo (MC) simulations are commonly used to study linear energy transfer (LET)
distributions in therapeutic proton beams. Various techniques have been used to score LET …

Fred: a GPU-accelerated fast-Monte Carlo code for rapid treatment plan recalculation in ion beam therapy

A Schiavi, M Senzacqua, S Pioli… - Physics in Medicine …, 2017 - iopscience.iop.org
Ion beam therapy is a rapidly growing technique for tumor radiation therapy. Ions allow for a
high dose deposition in the tumor region, while sparing the surrounding healthy tissue. For …

Site-specific range uncertainties caused by dose calculation algorithms for proton therapy

J Schuemann, S Dowdell, C Grassberger… - Physics in Medicine …, 2014 - iopscience.iop.org
The purpose of this study was to assess the possibility of introducing site-specific range
margins to replace current generic margins in proton therapy. Further, the goal was to study …

[图书][B] Monte Carlo techniques in radiation therapy

J Seco, F Verhaegen - 2013 - api.taylorfrancis.com
Monte Carlo simulation techniques made a slow entry in the field of radiotherapy in the late
1970s. Since then they have gained enormous popularity, judging by the number of papers …

Accurate Monte Carlo simulations for nozzle design, commissioning and quality assurance for a proton radiation therapy facility

H Paganetti, H Jiang, SY Lee, HM Kooy - Medical physics, 2004 - Wiley Online Library
Monte Carlo dosimetry calculations are essential methods in radiation therapy. To take full
advantage of this tool, the beam delivery system has to be simulated in detail and the initial …

Effects of Hounsfield number conversion on CT based proton Monte Carlo dose calculations

H Jiang, J Seco, H Paganetti - Medical physics, 2007 - Wiley Online Library
The Monte Carlo method provides the most accurate dose calculations on a patient
computed tomography (CT) geometry. The increase in accuracy is, at least in part, due to the …

Monte Carlo simulations to support start-up and treatment planning of scanned proton and carbon ion therapy at a synchrotron-based facility

K Parodi, A Mairani, S Brons, BG Hasch… - Physics in Medicine …, 2012 - iopscience.iop.org
Reliable treatment planning of highly conformal scanned ion beam therapy demands
accurate tools for the determination and characterization of the individual pencil-like beams …

A Monte Carlo pencil beam scanning model for proton treatment plan simulation using GATE/GEANT4

L Grevillot, D Bertrand, F Dessy, N Freud… - Physics in Medicine & …, 2011 - iopscience.iop.org
This work proposes a generic method for modeling scanned ion beam delivery systems,
without simulation of the treatment nozzle and based exclusively on beam data library (BDL) …

Adaptation of GEANT4 to Monte Carlo dose calculations based on CT data: Monte Carlo dose calculations based on CT data

H Jiang, H Paganetti - Medical physics, 2004 - Wiley Online Library
The geant4 Monte Carlo code provides many powerful functions for conducting particle
transport simulations with great reliability and flexibility. However, as a general purpose …