Rationale Intra-striatal infusions of the muscarinic antagonist, scopolamine, markedly
suppress feeding; however, the underlying mechanisms are unclear. Recent findings …

Intra-nucleus accumbens (Acb) infusion of cholinergic muscarinic antagonist, scopolamine
(10μg/0.5 μl), markedly reduced fat intake elicited by intra-Acb treatment of the μ-opioid …

Frontal cortical regions are activated by food-associated stimuli, and this activation appears
to be dysregulated in individuals with eating disorders. Nevertheless, frontal control of basic …

Evidence suggests that brain opioid receptorrs of the mu, delta and kappa subtypes may be
involved in the control of feeding behavior. However, limited information is available …

The present study examined opioid receptor (s) mediation of feeding elicited by mu opioid
agonists in the ventral tegmental area using general or selective opioid antagonist …

Previous work has shown that morphine infusion into the ventral striatum results in marked
hyperphagia in satiated rats. The present investigation was undertaken to determine the …

Both systemic and intracranial administration of morphine can result in spontaneous feeding
in nondeprived rats. The present investigation was conducted to examine the involvement of …

Stimulation of mu opioid receptors using drugs like morphine can increase eating when
injected into multiple brain regions including the lateral septum (LS). The LS has been …

Multiple laboratories have shown that the stimulation of μ-opioid receptors in the nucleus
accumbens (NAcc) powerfully increases intake of palatable and high-fat diets. Separate …

Rationale: Endogenous opioids have been implicated in the hedonic evaluation of food and
palatability. Opioids may also be involved in alcohol intake, as there is a positive correlation …