Chemical inhibition of neurons in the nucleus accumbens shell (AcbSh) elicits intense,
behaviorally specific, feeding in satiated rats. We have demonstrated previously that this …

It has previously been demonstrated that stimulation of opiate receptors within the nucleus
accumbens results in marked hyperphagia, perhaps reflecting enhancement of taste …

Rats suppress intake of a saccharin cue when paired with a drug of abuse such as morphine
or cocaine. Relative to Lewis rats, Fischer rats exhibit greater avoidance of a saccharin cue …

Rationale Acute pharmacological studies implicate μ-opioid receptors (MORs) in the
parabrachial nucleus (PBN) of the brainstem in modulating eating. The long-term effects of …

A previous in vivo autoradiographic study demonstrated reduced 3 H-diprenorphine binding
in anterior cingulate cortex of rats that were injected (iv) with the radiolabeled opiate during …

Opioid receptor subtype antagonists differentially alter food intake under deprivation (24 h),
glucoprivic (2-deoxy-d-glucose, 500 mg/kg, ip) or palatable (10% sucrose) conditions with μ …

Endogenous opioids, and in particular μ-opioid receptors, have been linked to hedonic and
rewarding mechanisms engaged during palatable food intake. The aim of this study was to …

Opioids induce rewarding and locomotor effects by inhibiting rostromedial tegmental GABA
neurons that express μ‐opioid and nociceptin receptors. These GABA neurons then strongly …

Rationale Previous work has shown that stimulation of GABAergic, opioid, or dopaminergic
systems within the nucleus accumbens modulates food intake and food-seeking behavior …

Ventricular microinjection studies found that whereas μ (β-funaltrexamine, B-FNA), μ1
(naloxonazine) and κ (nor-binaltorphamine, Nor-BNI) opioid receptor antagonists, but not δ …