Infusion of a μ-opioid receptor (MOR) agonist into the nucleus accumbens (NAcc) drives
voracious food intake, an effect hypothesized to occur through increased tastant palatability …

Centrally applied opioids delay gastric emptying and inhibit intestinal transit. However, the
mechanism of inhibitory effects of central opioids on gastric motility still remains unclear. It …

Previous studies have localized a central pattern generator for mastication to the midline
pontomedullary reticular formation (RF) based on cortically induced ororhythmic …

Endogenous opioid peptides within the nucleus accumbens, a forebrain site critical for the
regulation of reward-related behavior, are believed to play an important role in the control of …

The nucleus accumbens shell region (sNAcc) and the ventral tegmental area (VTA) are two
major nodes in the mesolimbic dopamine pathway, which mediates reward for various …

BACKGROUND: There is much interest in exploring whether reward-driven feeding can
produce druglike plasticity in the brain. The gamma-aminobutyric acid (GABA) system in the …

The corticostriatal pathway is believed to utilize the excitatory amino acid glutamate as its
transmitter, and the striatum contains high levels of all glutamate receptor subtypes. It has …

Various aspects of feeding behavior (eg consumption, motivation and anticipation) are
regulated by homeostatic and hedonic systems, and are modulated by dopaminergic and …

Food-deprived rats received microinjections of the preferential μ opiate morphine or the
selective κ opiate U-50,488 H (0.1, 1 and 10 nmol) into the ventral tegmental area (VTA) …

Rationale The nonselective muscarinic antagonist scopolamine hydrobromide (SCOP) is
employed as the gold standard for inducing memory impairments in healthy humans and …