Serum levels of glycosyltransferases and related glycoproteins as indicators of cancer: biological and clinical implications

MM Weiser, JR Wilson, D Kessel - CRC Critical Reviews in Clinical …, 1981 - Taylor & Francis
In this article data implying that there are significant changes in glycoprotein synthesis
associated with malignant transformation and cellular differentiation are reviewed. This …

Glycosyltransferases in cancer

MM Weiser, WD Klohs, DK Podolsky… - The …, 2012 - books.google.com
Glycosyltransferases, which are membrane-bound enzymes in the cell, are detected as
soluble activities in serum and other body fluids (Wagner and Cyn-kin, 1971; Kim et al …

Glycosyltransferase levels in tumors metastatic to liver and in uninvolved liver tissue

D Kessel, E Sykes, M Henderson - Journal of the National …, 1977 - academic.oup.com
Elevated levels of three plasma glycosyltransferases were associated with neoplasia in
cancer patients, notably those with tumor metastatic to liver. We examined levels of …

Cancer‐associated elevation of α (1→ 3)‐l‐fucosyltransferase activity in human serum

S Yazawa, R Madiyalakan, KL Matta, H Izawa, T Asao… - Cancer, 1988 - Wiley Online Library
GDP‐fucose: N‐acetylglucosaminide α (1→ 3)‐L‐fucosyltransferase activity was measured
in sera of patients with various cancers using a synthetic substrate, N‐acetyl‐2′‐O …

Glycosyltransferase and glycosidase activities in ovarian cancer patients

SK Chatterjee, M Bhattacharya, JJ Barlow - Cancer research, 1979 - AACR
In order to elucidate the mechanism of appearance of abnormal glycoproteins in cancer,
activities of glycoprotein glycosyltransferases and glycosidases were determined in the …

Serum glycoproteins and malignant neoplastic disorders

H Bacchus - CRC Critical reviews in clinical laboratory sciences, 1977 - Taylor & Francis
Several disease processes are characterized by alterations in the plasma levels of
glycoprotein substances.'-'Elevated circulating levels of these pro te in-ca rbohydrate …

Critical comments on galactosyltransferase.

AL Pohl - Cancer Detection and Prevention, 1984 - europepmc.org
Galactosyltransferase (GT) is reported to be a good marker for a number of malignancies.
Analytical and preparative attempts to characterize the more specific tumor-associated GT II …

Alterations in glycosyltransferase activity in human colon cancer

JT LaMont, KJ Isselbacher - Journal of the national cancer …, 1975 - academic.oup.com
Glycosyltransferase enzymes were measured in homogenates of normal and neoplastic
colon epithelium. The levels for exogenous galactosyltransferase and fucosyltransferase …

Glycosyltransferase and glycosidase activities in cultured human fetal and colonic adenocarcinoma cell lines

JS Whitehead, FJ Fearney, YS Kim - Cancer Research, 1979 - AACR
Three galactosyltransferases, an N-acetylgalactosaminyltransferase, two sialyltransferases,
and glycosidase activities were examined in cultured human colonic fetal and tumor cells …

Purification of galactosyltransferase'isoenzymes' I and II. Comparison of cancer associated and normal galactosyltransferase activities

DK Podolsky, MM Weiser - Journal of …, 1979 - utsouthwestern.pure.elsevier.com
Pooled effusions from patients with various cancers were used as an enzyme source for
purification of both the cancer-associated galactosyltransferase (GT-II) and the normal …