A bifunctional DNA intercalating agent 7V, A-(4, 4'-oxydibenzyl) bis (phenanthridinium
chloride)(9) has been synthesized. Interaction of this compound with DNA has been …

Several aspects of the intercalation of organic dyes into DNA are presented. After a
description of general features of intercalation and the analytical evaluation of this binding …

The non-covalent binding of the cationic reagent lucigenin to DNA has been investigated by
spectroscopic methods. Results from absorption, circular dichroism, and fluorescence …

Several planar aromatic molecules are known to intercalate between base pairs of double-
stranded DNA. This mode of interaction has been used to stain DNA as well as to load drug …

A variety of molecules bind to DNA in its major and minor grooves, and some, like the
anthraquinoids, are known to form intercalates in which these molecules are inserted …

Revised Manuscript Received October 28, 1988 abstract: Unfused tricyclic aromatic ring
systems 1-6 with one or two cationic side chains have been synthesized and their …

1-Methyl-γ-carboline derivatives were transformed into the corresponding N-aminoazinium
salts, which were condensed with 1, 2-dicarbonyl compounds (Westphal reaction) to afford …

DNA intercalating agents interfere with DNA's role as a template in replication and
transcription by inserting an intercalator molecule between adjacent base pairs. We …

Considerable attention has focused on new DNA-binding and-modifying agents, from
natural products to wholly synthetic designs, as probes of DNA structure and as po-tential …

The effect of twelve novel imidazolyl derivatives of 1, 8-acridinedione (ligands) on calf
thymus DNA was studied applying different biophysical techniques including UV-Vis …