Objective Health or disease is shaped for all individuals by interactions between their genes
and environment. Exactly how the environment changes gene expression and how this can …

Over the past two decades, the applications of genetic and genomic technologies have
begun to transform research questions and practices within epidemiology and toxicology …

Purpose Despite accumulating evidence from experimental animal studies showing that
paternal environmental exposures induce genetic and epigenetic alterations in sperm which …

The long-term consequences of early environmental experiences for development have
been explored extensively in animal models to better understand the mechanisms mediating …

The developmental origins of health and disease (DOHaD) approach has evolved over the
past 20 years, and the current hypothesis proposes that fetal adaptations to intrauterine and …

In humans, studies based on Developmental Origins of Health and Disease (DOHaD)
concept and targeting short half-lived chemicals, including many endocrine disruptors …

The growing field of 'Developmental Origin of Health and Disease'(DOHaD) generally
reflects environmental influences from mother to child. The importance of maternal lifestyle …

To advance our knowledge of the influence of environmental exposures on human health
and disease, robust studies are needed. However, for many exposures, robust studies are …

Abstract The Developmental Origins of Health and Disease (DOHaD) paradigm is one of the
most rapidly expanding areas of biomedical research. Environmental stressors that can …

The health consequences of material deficiency (eg, extreme malnutrition or lack of water or
inadequate clothing and shelter) have been long known. 1 However, recently, a new, more …