Applications of positron emission tomography in the development of molecular targeted cancer therapeutics
For molecular targeted cancer therapies to fulfill their promise in cancer treatment,
innovative approaches are required to overcome significant obstacles that exist in the …
innovative approaches are required to overcome significant obstacles that exist in the …
Positron emission tomography imaging of small animals in anticancer drug development
EO Aboagye - Molecular Imaging and Biology, 2005 - Springer
Positron emission tomography (PET) imaging of small animals enables researchers to
bridge the gap between in vitro science and in vivo human studies. The imaging paradigm …
bridge the gap between in vitro science and in vivo human studies. The imaging paradigm …
Positron emission tomography (PET): expanding the horizons of oncology drug development
LA Hammond, L Denis, U Salman, P Jerabek… - Investigational new …, 2003 - Springer
Positron emission tomography (PET) allows three-dimensional quantitative determination of
the distribution of radioactivity permitting measurement of physiological, biochemical, and …
the distribution of radioactivity permitting measurement of physiological, biochemical, and …
Molecular imaging of targeted therapies with positron emission tomography: the visualization of personalized cancer care
LH Mammatas, HMW Verheul, NH Hendrikse… - Cellular Oncology, 2015 - Springer
Introduction Molecular imaging has been defined as the visualization, characterization and
measurement of biological processes at the molecular and cellular level in humans and …
measurement of biological processes at the molecular and cellular level in humans and …
Clinical translation of molecular imaging agents used in PET studies of cancer
LM Kenny, EO Aboagye - Advances in cancer research, 2014 - Elsevier
Over recent years, there has been a rapid expansion in our knowledge of the factors that
regulate tumor growth; this has resulted in the identification of new therapeutic targets and …
regulate tumor growth; this has resulted in the identification of new therapeutic targets and …
Positron emission tomography: applications in drug discovery and drug development
J Wang, L Maurer - Current topics in medicinal chemistry, 2005 - ingentaconnect.com
Positron Emission Tomography (PET) is a sophisticated nuclear imaging modality that
affords researchers the ability to conduct both functional and molecular imaging on …
affords researchers the ability to conduct both functional and molecular imaging on …
Pet oncological radiopharmaceuticals: Current status and perspectives
M Lin, RP Coll, AS Cohen, DK Georgiou, HC Manning - Molecules, 2022 - mdpi.com
Molecular imaging is the visual representation of biological processes that take place at the
cellular or molecular level in living organisms. To date, molecular imaging plays an …
cellular or molecular level in living organisms. To date, molecular imaging plays an …
Radiolabelled tracers and anticancer drugs for assessment of therapeutic efficacy using PET
F Brady, SK Luthra, GD Brown, S Osman… - Current …, 2001 - ingentaconnect.com
Positron Emission Tomography (PET) has the potential to improve efficacy of established
and novel cancer therapies and to assist more rapid and rational progression of promising …
and novel cancer therapies and to assist more rapid and rational progression of promising …
Clinical molecular imaging with positron emission tomography
Molecular imaging allows for the in vivo evaluation of targeted molecules and biological
processes in man. Positron emission tomography (PET) is a highly sensitive and quantitative …
processes in man. Positron emission tomography (PET) is a highly sensitive and quantitative …
Developing new molecular imaging probes for PET
K Serdons, A Verbruggen, GM Bormans - Methods, 2009 - Elsevier
Positron emission tomography (PET) is a fully translational molecular imaging technique that
requires specific probes radiolabelled with short-lived positron emitting radionuclides. This …
requires specific probes radiolabelled with short-lived positron emitting radionuclides. This …