Extracellular vesicles released from macrophages modulates interleukin-1β in astrocytic and neuronal cells
We have recently demonstrated that long-term exposure of cigarette smoke condensate
(CSC) to HIV-uninfected (U937) and-infected (U1) macrophages induce packaging of pro …
(CSC) to HIV-uninfected (U937) and-infected (U1) macrophages induce packaging of pro …
Extracellular vesicles containing IL-4 modulate neuroinflammation in a mouse model of multiple sclerosis
Extracellular vesicles (EVs) play a major role in cell-to-cell communication in physiological
and pathological conditions, and their manipulation may represent a promising therapeutic …
and pathological conditions, and their manipulation may represent a promising therapeutic …
Extracellular Vesicles Cargo in Modulating Microglia Functional Responses
Simple Summary Extracellular vesicles (EVs) are considered a new additional mechanism
of intercellular communication also in brain cells. Microglia are brain-resident immune cells …
of intercellular communication also in brain cells. Microglia are brain-resident immune cells …
Inflammation leads to distinct populations of extracellular vesicles from microglia
Y Yang, A Boza-Serrano, CJR Dunning… - Journal of …, 2018 - Springer
Background Activated microglia play an essential role in inflammatory responses elicited in
the central nervous system (CNS). Microglia-derived extracellular vesicles (EVs) are …
the central nervous system (CNS). Microglia-derived extracellular vesicles (EVs) are …
Differential packaging of inflammatory cytokines/chemokines and oxidative stress modulators in U937 and U1 macrophages-derived extracellular vesicles upon …
Smoking, which is highly prevalent in HIV-infected populations, has been shown to
exacerbate HIV replication, in part via the cytochrome P450 (CYP)-induced oxidative stress …
exacerbate HIV replication, in part via the cytochrome P450 (CYP)-induced oxidative stress …
Neuron-derived extracellular vesicles modulate microglia activation and function
Simple Summary In this study we investigated how neuron-derived extracellular vesicles
(NDEVs) mediate neuroimmune regulation in primary cell culture systems. Rat cortical …
(NDEVs) mediate neuroimmune regulation in primary cell culture systems. Rat cortical …
Tissue and stem cell sourced extracellular vesicle communications with microglia
SE Spellicy, SL Stice - Stem Cell Reviews and Reports, 2021 - Springer
Abstract Extracellular vesicles (EVs), nano-to micro-sized vesicles released from cells, have
garnered attention in recent years for their role in intercellular communication. Specifically …
garnered attention in recent years for their role in intercellular communication. Specifically …
Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis
CM Willis, AM Nicaise, A Menoret… - Proceedings of the …, 2019 - National Acad Sciences
Extracellular vesicles (EVs) are emerging as potent mediators of intercellular communication
with roles in inflammation and disease. In this study, we examined the role of EVs from blood …
with roles in inflammation and disease. In this study, we examined the role of EVs from blood …
Identification of a novel mechanism of blood–brain communication during peripheral inflammation via choroid plexus‐derived extracellular vesicles
S Balusu, E Van Wonterghem, R De Rycke… - EMBO molecular …, 2016 - embopress.org
Here, we identified release of extracellular vesicles (EVs) by the choroid plexus epithelium
(CPE) as a new mechanism of blood–brain communication. Systemic inflammation induced …
(CPE) as a new mechanism of blood–brain communication. Systemic inflammation induced …
Molecular and cellular impact of inflammatory extracellular vesicles (EVs) derived from M1 and M2 macrophages on neural action potentials
S Vakili, TM Ahooyi, SS Yarandi, M Donadoni… - Brain sciences, 2020 - mdpi.com
Several factors can contribute to neuroinflammatory disorders, such as cytokine and
chemokines that are produced and released from peripherally derived immune cells or from …
chemokines that are produced and released from peripherally derived immune cells or from …
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