Purpose Real‐world evidence (RWE) includes data from retrospective or prospective
observational studies and observational registries and provides insights beyond those …

Objectives Ambiguity in communication of key study parameters limits the utility of real-world
evidence (RWE) studies in healthcare decision-making. Clear communication about data …

Abstract Objective In both the United States and Europe there has been an increased
interest in using comparative effectiveness research of interventions to inform health policy …

The analysis of longitudinal healthcare data outside of highly controlled parallel‐group
randomized trials, termed real‐world evidence (RWE), has received increasing attention in …

Doctors, patients, and other decision makers need access to the best available clinical
evidence, which can come from systematic reviews, experimental trials, and observational …

Findings from clinical trials cannot be generalized to population at large due to the stringent
eligibility criteria. RWE studies complement clinical trials by generalizing the findings from …

Evidence from medication use in the real world setting can help to extrapolate and/or
augment data obtained in randomized controlled trials and establishes a broad picture of a …

The 21st Century Cures Act passed by the United States Congress mandates the US Food
and Drug Administration to develop guidance to evaluate the use of real‐world evidence …

Real-world studies have become increasingly important in providing evidence of treatment
effectiveness in clinical practice. While randomized clinical trials (RCTs) are the “gold …

Objectives To examine how real-world evidence (RWE) is currently perceived and used in
managed care environments, especially to inform pharmacy and therapeutic (P&T) …