Clinical evaluation of somatostatin use in pancreatic resections: Clinical efficacy or limited benefit?

RJ Anderson, E Dunki-Jacobs, GG Callender… - Surgery, 2013 - Elsevier
Background The benefit of somatostatin for the prevention of pancreatic fistula has been
debated widely in the literature. The aim of this study was to evaluate the efficacy of …

A cost analysis of somatostatin use in the prevention of pancreatic fistula after pancreatectomy

R Anderson, E Dunki-Jacobs, N Burnett… - World journal of …, 2014 - Springer
Background Studies have shown that somatostatin reduces the occurrence of postoperative
pancreatic fistula. However, no study to date has analyzed the cost effectiveness of this …

The effect of somatostatin and its analogs in the prevention of pancreatic fistula after elective pancreatic surgery

F Čečka, B Jon, Z Šubrt, A Ferko - European Surgery, 2012 - Springer
BACKGROUND: The prophylactic use of somatostatin and its analogs has been suggested
to lower the rate of pancreatic fistula. The aim of this review is to discuss the results of …

A randomised, multicentre trial of somatostatin to prevent clinically relevant postoperative pancreatic fistula in intermediate-risk patients after …

Z Cao, J Qiu, J Guo, G Xiong, K Jiang, S Zheng… - Journal of …, 2021 - Springer
Background Prophylactic somatostatin to reduce the incidence of clinically relevant
postoperative pancreatic fistula after pancreaticoduodenectomy remains controversial. We …

Are somatostatin or its synthetic analogues helpful in reducing pancreatic fistula?

E Angst, B Gloor - Digestive surgery, 2013 - karger.com
Pancreatic surgery is associated with a high morbidity. One of the most frequently seen
major complications is a pancreatic leak or fistula [1]. The incidence of pancreatic leaks …

Meta-analysis of the value of somatostatin and its analogues in reducing complications associated with pancreatic surgery

S Connor, N Alexakis, OJ Garden… - Journal of British …, 2005 - academic.oup.com
Background The role of somatostatin and its analogues in reducing complications after
pancreatic resection is controversial. This is a meta-analysis of the evidence of benefit …

Does prophylactic administration of somatostatin decrease the rates of complications after pancreatic resection?: a clinical and electron microscopy study

A Katsourakis, P Zezos, G Noussios, G Kouklakis… - Pancreas, 2013 - journals.lww.com
Objectives The postoperative morbidity after pancreatectomy remains high. The role of
somatostatin and its analogs in reducing complications after pancreatic resection is …

Systematic review and meta-analysis of somatostatin analogues in the prevention of postoperative complication after pancreaticoduodenectomy

K Jin, H Zhou, J Zhang, W Wang, Y Sun, C Ruan… - Digestive …, 2015 - karger.com
Background: The use of somatostatin analogues (SAs) following pancreaticoduodenectomy
(PD) is controversial. Method: Literature databases were searched systematically for …

Somatostatin analogues and the risk of post-operative pancreatic fistulas after pancreatic resection-A systematic review & meta-analysis

T Li, RT D'Cruz, SY Lim, VG Shelat - Pancreatology, 2020 - Elsevier
Background Post-operative pancreatic fistula (POPF) is a common complication of
pancreatic resection. Somatostatin analogues (SA) have been used as prophylaxis to …

[HTML][HTML] Somatostatin analogues for the prevention of pancreatic fistula after open pancreatoduodenectomy: A nationwide analysis

BT Bootsma, VD Plat, T van de Brug, DE Huisman… - Pancreatology, 2022 - Elsevier
Background Somatostatin analogues (SA) are currently used to prevent postoperative
pancreatic fistula (POPF) development. However, its use is controversial. This study …