[HTML][HTML] Therapeutic peptides: Historical perspectives, current development trends, and future directions
JL Lau, MK Dunn - Bioorganic & medicinal chemistry, 2018 - Elsevier
Peptide therapeutics have played a notable role in medical practice since the advent of
insulin therapy in the 1920s. Over 60 peptide drugs are approved in the United States and …
insulin therapy in the 1920s. Over 60 peptide drugs are approved in the United States and …
Trends in peptide drug discovery
Since the introduction of insulin almost a century ago, more than 80 peptide drugs have
reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis …
reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis …
[HTML][HTML] Peptide therapeutics: current status and future directions
K Fosgerau, T Hoffmann - Drug discovery today, 2015 - Elsevier
Highlights•We provide a SWOT analysis of peptide therapeutics and discuss commercial
aspects.•We comment on emerging peptide technologies and cell-penetrating peptides.• …
aspects.•We comment on emerging peptide technologies and cell-penetrating peptides.• …
The current state of peptide drug discovery: back to the future?
A Henninot, JC Collins, JM Nuss - Journal of medicinal chemistry, 2018 - ACS Publications
Over the past decade, peptide drug discovery has experienced a revival of interest and
scientific momentum, as the pharmaceutical industry has come to appreciate the role that …
scientific momentum, as the pharmaceutical industry has come to appreciate the role that …
Therapeutic peptides: current applications and future directions
L Wang, N Wang, W Zhang, X Cheng, Z Yan… - Signal transduction and …, 2022 - nature.com
Peptide drug development has made great progress in the last decade thanks to new
production, modification, and analytic technologies. Peptides have been produced and …
production, modification, and analytic technologies. Peptides have been produced and …
Peptide-based drug discovery: Current status and recent advances
Highlights•A comprehensive compilation and analysis of FDA approved and under clinical
trials peptide-based therapeutics.•Clinical trial peptides pipeline analysis reveals emerging …
trials peptide-based therapeutics.•Clinical trial peptides pipeline analysis reveals emerging …
Therapeutic peptides
F Albericio, HG Kruger - Future medicinal chemistry, 2012 - Taylor & Francis
The analysis of these peptides by therapeutic categories is an indication of the versatility of
peptides to tackle a large number of biochemical transgressions. Thus, boceprevir and …
peptides to tackle a large number of biochemical transgressions. Thus, boceprevir and …
Peptide therapeutics and the pharmaceutical industry: barriers encountered translating from the laboratory to patients
J Rafferty, H Nagaraj, AP McCloskey… - Current medicinal …, 2016 - ingentaconnect.com
Peptides are receiving increasing interest as clinical therapeutics. These highly tunable
molecules can be tailored to achieve desirable biocompatibility and biodegradability with …
molecules can be tailored to achieve desirable biocompatibility and biodegradability with …
Synthetic therapeutic peptides: science and market
P Vlieghe, V Lisowski, J Martinez, M Khrestchatisky - Drug discovery today, 2010 - Elsevier
The decreasing number of approved drugs produced by the pharmaceutical industry, which
has been accompanied by increasing expenses for R&D, demands alternative approaches …
has been accompanied by increasing expenses for R&D, demands alternative approaches …
Peptide therapeutics 2.0
BG de la Torre, F Albericio - 2020 - digital.csic.es
Peptide Therapeutics 2.0 Page 1 molecules Editorial Peptide Therapeutics 2.0 Beatriz G. de la
Torre 1,* and Fernando Albericio 2,3,4,* 1 KwaZulu-Natal Research Innovation and …
Torre 1,* and Fernando Albericio 2,3,4,* 1 KwaZulu-Natal Research Innovation and …