Cervical cancer cell–derived angiopoietins promote tumor progression
P Yang, N Chen, D Yang, J Crane, B Huang… - Tumor …, 2017 - journals.sagepub.com
Metastatic or recurrent cervical cancer has limited treatment options and a high rate of
mortality. Although anti-vascular endothelial growth factor drugs have shown great promise …
mortality. Although anti-vascular endothelial growth factor drugs have shown great promise …
[HTML][HTML] TIE2-high cervical cancer cells promote tumor angiogenesis by upregulating TIE2 and VEGFR2 in endothelial cells
S Tan, Y Chen, S Du, W Li, P Liu, J Zhao, P Yang… - Translational …, 2022 - Elsevier
Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 2
(TIE2), the receptor for angiopoietins, has been found highly expressed in cervical cancer …
(TIE2), the receptor for angiopoietins, has been found highly expressed in cervical cancer …
Angiopoietin 1 promotes tumor angiogenesis and tumor vessel plasticity of human cervical cancer in mice
Angiopoietins have been increasingly implicated to play important roles in blood vessel
formation, remodeling, maturation, and maintenance. However, their roles in tumor …
formation, remodeling, maturation, and maintenance. However, their roles in tumor …
[PDF][PDF] Angiopoietin-1 is associated with a decreased risk of lymph node metastasis in early stage cervical cancer
E Cai, D Yang, Y Zhang, J Cai, S Sun, P Yang… - 2020 - hh.um.es
Objectives. Lymph node metastasis (LNM) is an important determinant of prognosis in
patients with cervical cancer. Members of the angiopoietin family have been demonstrated …
patients with cervical cancer. Members of the angiopoietin family have been demonstrated …
Role of angiopoietins in development of cancer and neoplasia associated with viral infection
X Yu, F Ye - Cells, 2020 - mdpi.com
Angiopoietin/tyrosine protein kinase receptor Tie-2 signaling in endothelial cells plays an
essential role in angiogenesis and wound healing. Angiopoietin-1 (Ang-1) is crucial for …
essential role in angiogenesis and wound healing. Angiopoietin-1 (Ang-1) is crucial for …
The ratio of serum Angiopoietin-1 to Angiopoietin-2 in patients with cervical cancer is a valuable diagnostic and prognostic biomarker
P Yang, N Chen, D Yang, J Crane, S Yang, H Wang… - PeerJ, 2017 - peerj.com
Objectives Angiopoietins have been found to play essential roles in tumor angiogenesis.
The present study was aimed at investigating the diagnostic and prognostic values of serum …
The present study was aimed at investigating the diagnostic and prognostic values of serum …
[PDF][PDF] Plasma concentration of angiopoietin-1, angiopoietin-2 and Tie-2 in cervical cancer
E Kopczynska, R Makarewicz, M Biedka… - Eur. J. Gynaec …, 2009 - article.imrpress.com
Purpose of investigation: Angiogenesis is important in the promotion and progression of
malignancy. The formation of new blood vessels is coordinated by many factors …
malignancy. The formation of new blood vessels is coordinated by many factors …
Specifically targeting angiopoietin-2 inhibits angiogenesis, Tie2-expressing monocyte infiltration, and tumor growth
H Huang, JY Lai, J Do, D Liu, L Li, J Del Rosario… - Clinical Cancer …, 2011 - AACR
Abstract Purpose: Angiopoietin-1 (Ang1) plays a key role in maintaining stable vasculature,
whereas in a tumor Ang2 antagonizes Ang1's function and promotes the initiation of the …
whereas in a tumor Ang2 antagonizes Ang1's function and promotes the initiation of the …
The dynamic roles of angiopoietins in tumor angiogenesis
Q Yu - Future oncology, 2005 - Taylor & Francis
Angiopoietin (Ang)-1 and-2, and mouse Ang-3/human Ang-4 are ligands of the receptor
tyrosine kinase with immunoglobulin and epidermal growth factor homology domains (Tie) …
tyrosine kinase with immunoglobulin and epidermal growth factor homology domains (Tie) …
Involvement of angiopoietins in cancer progression in association with cancer cell-fibroblast interaction
E Maruyama, T Sakamoto, H Azuma, Y Ito… - Anticancer …, 2005 - ar.iiarjournals.org
Purpose: The role of angiopoietins (ANGs) in cancer progression is a new field of research.
We examined the patterns of expression of ANGs in human renal cancer tissues (n= 12) and …
We examined the patterns of expression of ANGs in human renal cancer tissues (n= 12) and …
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