INTRODUCTION Under homeostasis, the central nervous system (CNS) hosts microglia
(MG) and CNS-associated macrophages (CAMs). During experimental autoimmune …

As immune sentinels of the central nervous system (CNS), microglia not only respond
rapidly to pathological conditions but also contribute to homeostasis in the healthy brain. In …

Inflammation is a hallmark of different central nervous system (CNS) pathologies. It has been
linked to neurodegenerative disorders as well as primary and metastatic brain tumors …

In neurological diseases, the actions of microglia, the resident myeloid cells of the CNS
parenchyma, may diverge from, or intersect with, those of recruited monocytes to drive …

Neuroinflammation and neurodegeneration may represent two poles of brain pathology.
Brain myeloid cells, particularly microglia, play key roles in these conditions. We employed …

Microglia are specialized parenchymal‐resident phagocytes of the central nervous system
(CNS) that actively support, defend and modulate the neural environment. Dysfunctional …

Microglia are the resident immune effector cells of the central nervous system (CNS) rapidly
reacting to various pathological stimuli to maintain CNS homeostasis. However, microglial …

Specialized populations of tissue-resident myeloid cells inhabit every organ of the body.
While many of these populations appear similar morphologically and phenotypically, they …

The innate immune compartment of the human central nervous system (CNS) is highly
diverse and includes several immune-cell populations such as macrophages that are …

The immune system of the central nervous system (CNS) consists primarily of innate
immune cells. These are highly specialized macrophages found either in the parenchyma …