The diseased brain hosts a heterogeneous population of myeloid cells, including
parenchymal microglia, perivascular cells, meningeal macrophages and blood-borne …

Myeloid cells in the central nervous system (CNS) represent a heterogeneous class of
innate immune cells that contribute to the maintenance of tissue homeostasis differentially …

Microglia are parenchymal macrophages of the CNS; as professional phagocytes they are
important for maintenance of the brain's physiology. These cells are generated through …

Microglia and central nervous system (CNS)-associated macrophages (CAMs), such as
perivascular and meningeal macrophages, are implicated in virtually all diseases of the …

Oligodendrocyte dysfunction has been implicated in the pathogenesis of neurodegenerative
diseases, so understanding oligodendrocyte activation states would shed light on disease …

Along with microglia and monocyte-derived macrophages, macrophages in the perivascular
space, choroid plexus, and meninges are the principal effector cells in neuroinflammatory …

The immune system's role is much more than merely recognizing self vs. non-self and
involves maintaining homeostasis and integrity of the organism starting from early …

Background Multiple sclerosis (MS), an autoimmune disease of the central nervous system
(CNS), can be suppressed in its early stages but eventually becomes clinically progressive …

Microglia are resident immune cells in the central nervous system and play critical roles in in
brain immunity, development and homeostasis. The pathology of Alzheimer disease (AD) …

Microglia play an essential role in maintaining central nervous system (CNS) homeostasis,
as well as responding to injury and disease. Most neurological disorders feature microglial …