Role of ferroptosis in fibrotic diseases

J Zhou, Y Tan, R Wang, X Li - Journal of Inflammation Research, 2022 - Taylor & Francis
Ferroptosis is a unique and pervasive form of regulated cell death driven by iron-dependent
phospholipid peroxidation. It results from disturbed cellular metabolism and imbalanced …

Ferroptosis as an emerging therapeutic target in liver diseases

Y Lu, J Hu, L Chen, S Li, M Yuan, X Tian… - Frontiers in …, 2023 - frontiersin.org
Ferroptosis is an iron-dependently nonapoptotic cell death characterized by excessive
accumulation of lipid peroxides and cellular iron metabolism disturbances. Impaired iron …

Ferroptosis in colorectal cancer: a future target?

H Yan, R Talty, O Aladelokun, M Bosenberg… - British Journal of …, 2023 - nature.com
Colorectal cancer (CRC) is the third leading cause of cancer deaths worldwide and is
characterised by frequently mutated genes, such as APC, TP53, KRAS and BRAF. The …

Targeting ferroptosis in gastric cancer: Strategies and opportunities

J Le, G Pan, C Zhang, Y Chen, AK Tiwari… - Immunological …, 2024 - Wiley Online Library
Ferroptosis is a novel form of programmed cell death morphologically, genetically, and
biochemically distinct from other cell death pathways and characterized by the accumulation …

Ferroptosis in liver diseases: an overview

MM Capelletti, H Manceau, H Puy… - International journal of …, 2020 - mdpi.com
Ferroptosis is an iron-dependent form of cell death characterized by intracellular lipid
peroxide accumulation and redox imbalance. Ferroptosis shows specific biological and …

Mechanisms and regulations of ferroptosis

XD Zhang, ZY Liu, MS Wang, YX Guo… - Frontiers in …, 2023 - frontiersin.org
Regulation of cell mortality for disease treatment has been the focus of research. Ferroptosis
is an iron-dependent regulated cell death whose mechanism has been extensively studied …

Managing ferroptosis-related diseases with indirect dietary modulators of ferroptosis

L Cao, S Zhao, K Han, L Fan, C Zhao, S Yin… - The Journal of Nutritional …, 2023 - Elsevier
Ferroptosis is an iron-dependent form of programmed cell death driven by excessive
oxidation of polyunsaturated phospholipids on cellular membranes. Accumulating evidence …

[PDF][PDF] Ferroptosis: principles and significance in health and disease

F Chen, R Kang, D Tang, J Liu - Journal of Hematology & Oncology, 2024 - Springer
Ferroptosis, an iron-dependent form of cell death characterized by uncontrolled lipid
peroxidation, is governed by molecular networks involving diverse molecules and …

The emerging role of ferroptosis in sepsis

Y Liu, S Tan, Y Wu, S Tan - DNA and cell biology, 2022 - liebertpub.com
Ferroptosis is a novel form of cell death characterized by the iron-dependent accumulation
of lipid peroxides and is different from other types of cell death. The mechanisms of …

Ferroptosis and necroinflammation, a yet poorly explored link

B Proneth, M Conrad - Cell Death & Differentiation, 2019 - nature.com
Ferroptosis is a non-apoptotic form of cell death characterized by overwhelming iron-
dependent lipid peroxidation, which contributes to a number of pathologies, most notably …