[HTML][HTML] Inducing iPSCs to escape the dish
B Barrilleaux, PS Knoepfler - Cell Stem Cell, 2011 - cell.com
Induced pluripotent stem cells (iPSCs) hold great promise for autologous cell therapies, but
significant roadblocks remain to translating iPSCs to the bedside. For example, concerns …
significant roadblocks remain to translating iPSCs to the bedside. For example, concerns …
[HTML][HTML] Molecular obstacles to clinical translation of iPSCs
N Tapia, HR Schöler - Cell stem cell, 2016 - cell.com
The ability to reprogram somatic cells into induced pluripotent stem cells (iPSCs) using
defined factors provides new tools for biomedical research. However, some iPSC clones …
defined factors provides new tools for biomedical research. However, some iPSC clones …
Induced pluripotent stem cells: The dragon awakens
W Han, Y Zhao, X Fu - BioScience, 2010 - academic.oup.com
Induced pluripotent stem cells (iPSCs) can be derived from many mouse and human
somatic cell types by forced expression of a small number of defined reprogramming factors …
somatic cell types by forced expression of a small number of defined reprogramming factors …
Overcoming barriers to the clinical utilization of iPSCs: reprogramming efficiency, safety and quality
S Cao, K Loh, Y Pei, W Zhang, J Han - Protein & cell, 2012 - Springer
Differentiated cells can be reprogrammed into pluripotent stem cells, known as “induced
pluripotent stem cells”(iPSCs), through the overexpression of defined transcription factors …
pluripotent stem cells”(iPSCs), through the overexpression of defined transcription factors …
Progress and promise towards safe induced pluripotent stem cells for therapy
The recent generation of induced pluripotent stem cells (iPSCs) from somatic cells provides
an invaluable resource for drug or toxicology screening, medical research, and patient …
an invaluable resource for drug or toxicology screening, medical research, and patient …
[HTML][HTML] Potential of induced pluripotent stem cells for use in gene therapy: History, molecular bases, and medical perspectives
A Fus-Kujawa, B Mendrek, A Trybus, K Bajdak-Rusinek… - Biomolecules, 2021 - mdpi.com
Induced pluripotent stem cells (iPSCs) are defined as reprogrammed somatic cells
exhibiting embryonic stem cell characteristics. Since their discovery in 2006, efforts have …
exhibiting embryonic stem cell characteristics. Since their discovery in 2006, efforts have …
[HTML][HTML] Inherent immunogenicity or lack thereof of pluripotent stem cells: implications for cell replacement therapy
A Chhabra - Frontiers in immunology, 2017 - frontiersin.org
Donor-specific induced pluripotent stem cells (iPSCs) offer opportunities for personalized
cell replacement therapeutic approaches due to their unlimited self-renewal potential and …
cell replacement therapeutic approaches due to their unlimited self-renewal potential and …
Modulation of human allogeneic and syngeneic pluripotent stem cells and immunological implications for transplantation
SD Sackett, ME Brown, DM Tremmel, T Ellis… - Transplantation …, 2016 - Elsevier
Tissues derived from induced pluripotent stem cells (iPSCs) are a promising source of cells
for building various regenerative medicine therapies; from simply transplanting cells to …
for building various regenerative medicine therapies; from simply transplanting cells to …
Applications of iPSCs in cancer research: supplementary issue: stem cell biology
JJ Kim - Biomarker insights, 2015 - journals.sagepub.com
Induced pluripotent stem cells (iPSCs) derived from reprogrammed somatic cells are
emerging as one of the most versatile tools in biomedical research and pharmacological …
emerging as one of the most versatile tools in biomedical research and pharmacological …
Cells derived from iPSC can be immunogenic—Yes or No?
J Cao, X Li, X Lu, C Zhang, H Yu, T Zhao - Protein & cell, 2014 - academic.oup.com
The induced pluripotent stem cells (iPSCs), derived by ectopic expression of reprogramming
factors in somatic cells, can potentially provide unlimited autologous cells for regenerative …
factors in somatic cells, can potentially provide unlimited autologous cells for regenerative …