Focal brain injuries (in particular, stroke and traumatic brain injury) induce with high
probability the development of delayed (months, years) cognitive and depressive …

Mood disorders associated with dysfunction of the hypothalamic–pituitary–adrenal (HPA)
axis are common psychiatric conditions. The glucocorticoid receptor (GR) is a steroid …

Depression is a serious psychiatric disorder that effects at least 350 million people
worldwide today. Dysregulation of the hypothalamic-pituitary-adrenal axis (HPAA) is a …

Hypothalamic–pituitary–adrenal (HPA) axis dysregulation has been proposed as a
neurobiological mechanism underlying the childhood adversity–psychosis link (Daskalakis …

Following the discovery of glucocorticoid receptors in the hippocampus and other brain
regions, research has focused on understanding the effects of glucocorticoids in the brain …

Previously, it has been suggested that hypothalamic‐pituitary‐adrenal (HPA) axis
dysregulation and, as a consequence, increased cortisol levels, is not only a state …

Chronic exposure to stress is associated with different behavioral and neurological
syndromes including impaired excitability of nerve cells in hippocampus (HIPPO) and …

BACKGROUND: Biological correlates of posttraumatic stress disorder (PTSD) have mostly
been studied using cross-sectional or posttrauma prospective designs. Therefore, it remains …

Glucocorticoids contribute fundamentally to the maintenance of basal and stress-related
homeostasis in all higher organisms. These hormones influence a large percentage of the …

Hyperactivity of the hypothalamus–pituitary–adrenal (HPA) axis and increased levels of
glucocorticoid hormones in patients with depression have mostly been ascribed to impaired …